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- Retinal_G_protein_coupled_receptor abstract "RPE-retinal G protein-coupled receptor is a protein that in humans is encoded by the RGR gene.Defects in this gene are a cause of retinitis pigmentosa. The gene is a member of the rhodopsin-like receptor subfamily of GPCR. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein presumably acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal, similar to retinochrome in invertebrates. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.".
- Retinal_G_protein_coupled_receptor entrezgene "5995".
- Retinal_G_protein_coupled_receptor wikiPageID "14626533".
- Retinal_G_protein_coupled_receptor wikiPageRevisionID "592929599".
- Retinal_G_protein_coupled_receptor hasPhotoCollection Retinal_G_protein_coupled_receptor.
- Retinal_G_protein_coupled_receptor requireManualInspection "no".
- Retinal_G_protein_coupled_receptor summaryText "Defects in this gene are a cause of retinitis pigmentosa. The gene is a member of the rhodopsin-like receptor subfamily of GPCR. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein presumably acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal, similar to retinochrome in invertebrates. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa . Alternative splicing results in multiple transcript variants encoding different isoforms.".
- Retinal_G_protein_coupled_receptor updateCitations "yes".
- Retinal_G_protein_coupled_receptor updatePage "yes".
- Retinal_G_protein_coupled_receptor updateProteinBox "yes".
- Retinal_G_protein_coupled_receptor updateSummary "no".
- Retinal_G_protein_coupled_receptor subject Category:G_protein_coupled_receptors.
- Retinal_G_protein_coupled_receptor type BodyPart105220461.
- Retinal_G_protein_coupled_receptor type GProteinCoupledReceptors.
- Retinal_G_protein_coupled_receptor type Part109385911.
- Retinal_G_protein_coupled_receptor type PhysicalEntity100001930.
- Retinal_G_protein_coupled_receptor type Receptor105608868.
- Retinal_G_protein_coupled_receptor type Structure105225602.
- Retinal_G_protein_coupled_receptor type Thing100002452.
- Retinal_G_protein_coupled_receptor type Biomolecule.
- Retinal_G_protein_coupled_receptor type Protein.
- Retinal_G_protein_coupled_receptor type BiologicalObject.
- Retinal_G_protein_coupled_receptor comment "RPE-retinal G protein-coupled receptor is a protein that in humans is encoded by the RGR gene.Defects in this gene are a cause of retinitis pigmentosa. The gene is a member of the rhodopsin-like receptor subfamily of GPCR. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein presumably acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal, similar to retinochrome in invertebrates.".
- Retinal_G_protein_coupled_receptor label "Retinal G protein coupled receptor".
- Retinal_G_protein_coupled_receptor sameAs m.03gr36s.
- Retinal_G_protein_coupled_receptor sameAs Q7316764.
- Retinal_G_protein_coupled_receptor sameAs Q7316764.
- Retinal_G_protein_coupled_receptor sameAs Retinal_G_protein_coupled_receptor.
- Retinal_G_protein_coupled_receptor wasDerivedFrom Retinal_G_protein_coupled_receptor?oldid=592929599.
- Retinal_G_protein_coupled_receptor isPrimaryTopicOf Retinal_G_protein_coupled_receptor.