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- Ridaforolimus abstract "Ridaforolimus (also known as AP23573 and MK-8669; formerly known as Deforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR, a protein that acts as a central regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival, integrating signals from proteins, such as PI3K, AKT and PTEN known to be important to malignancy. Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.It has had promising results in a clinical trial for advanced soft tissue and bone sarcoma.".
- Ridaforolimus atcPrefix "L01".
- Ridaforolimus atcSuffix "XE19".
- Ridaforolimus casNumber "572924-54-0".
- Ridaforolimus fdaUniiCode "48Z35KB15K".
- Ridaforolimus iupacName "(1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28Z,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl dimethylphosphinate".
- Ridaforolimus pubchem "11520894".
- Ridaforolimus thumbnail Deforolimus.svg?width=300.
- Ridaforolimus wikiPageExternalLink www.ariad.com.
- Ridaforolimus wikiPageID "16657724".
- Ridaforolimus wikiPageRevisionID "586762696".
- Ridaforolimus atcPrefix "L01".
- Ridaforolimus atcSuffix "XE19".
- Ridaforolimus c "53".
- Ridaforolimus casNumber "572924".
- Ridaforolimus chemspiderid "24597928".
- Ridaforolimus h "84".
- Ridaforolimus hasPhotoCollection Ridaforolimus.
- Ridaforolimus inchi "1".
- Ridaforolimus inchikey "BUROJSBIWGDYCN-GAUTUEMIBB".
- Ridaforolimus iupacName "-4".
- Ridaforolimus n "1".
- Ridaforolimus o "14".
- Ridaforolimus p "1".
- Ridaforolimus pubchem "11520894".
- Ridaforolimus smiles "CC1CCC2CCOC".
- Ridaforolimus stdinchi "1".
- Ridaforolimus stdinchikey "BUROJSBIWGDYCN-GAUTUEMISA-N".
- Ridaforolimus unii "48".
- Ridaforolimus verifiedfields "changed".
- Ridaforolimus verifiedrevid "464382356".
- Ridaforolimus watchedfields "changed".
- Ridaforolimus subject Category:Immunosuppressants.
- Ridaforolimus subject Category:Macrolides.
- Ridaforolimus type Agent114778436.
- Ridaforolimus type CausalAgent100007347.
- Ridaforolimus type Drug103247620.
- Ridaforolimus type Immunosuppressant103562958.
- Ridaforolimus type Immunosuppressants.
- Ridaforolimus type Matter100020827.
- Ridaforolimus type Medicine103740161.
- Ridaforolimus type PhysicalEntity100001930.
- Ridaforolimus type Substance100020090.
- Ridaforolimus type Drug.
- Ridaforolimus type DrugProduct.
- Ridaforolimus type FunctionalSubstance.
- Ridaforolimus comment "Ridaforolimus (also known as AP23573 and MK-8669; formerly known as Deforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR, a protein that acts as a central regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival, integrating signals from proteins, such as PI3K, AKT and PTEN known to be important to malignancy.".
- Ridaforolimus label "Ridaforolimus".
- Ridaforolimus label "Ridaforolimus".
- Ridaforolimus sameAs Ridaforolimus.
- Ridaforolimus sameAs m.03yk5wd.
- Ridaforolimus sameAs Q2151796.
- Ridaforolimus sameAs Q2151796.
- Ridaforolimus sameAs Ridaforolimus.
- Ridaforolimus wasDerivedFrom Ridaforolimus?oldid=586762696.
- Ridaforolimus depiction Deforolimus.svg.
- Ridaforolimus isPrimaryTopicOf Ridaforolimus.
