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- Rilonacept abstract "Rilonacept, also known as IL-1 Trap (marketed by Regeneron Pharmaceuticals under the trade name Arcalyst), is an interleukin 1 inhibitor.Rilonacept is a dimeric fusion protein consisting of the ligand-binding domains of the extracellular portions of the human interleukin-1 receptor component (IL-1R1) and IL-1 receptor accessory protein (IL-1RAcP) linked in-line to the fragment-crystallizable portion (Fc region) of human IgG1 that binds and neutralizes IL-1.Rilonacept was given an "Orphan Drug" status by the United States Food and Drug Administration and is used for the treatment of cryopyrin-associated periodic syndromes (CAPS), including familial cold autoinflammatory syndrome, Muckle-Wells syndrome and neonatal onset multisystem inflammatory disease(not approved in the U.S. on this indication).On May 8th, 2012 an FDA Advisory Panel voted 11-0 against the approval of rilonacept for the treatment of gout, stating that the benefits did not outweigh the risks associated with the drug.".
- Rilonacept atcPrefix "L04".
- Rilonacept atcSuffix "AC04".
- Rilonacept fdaUniiCode "8K80YB5GMG".
- Rilonacept iupacName "n/a".
- Rilonacept wikiPageExternalLink www.regeneron.com.
- Rilonacept wikiPageID "16305376".
- Rilonacept wikiPageRevisionID "592940611".
- Rilonacept atcPrefix "L04".
- Rilonacept atcSuffix "AC04".
- Rilonacept chembl "1201830".
- Rilonacept chemspiderid "NA".
- Rilonacept hasPhotoCollection Rilonacept.
- Rilonacept iupacName "n/a".
- Rilonacept legalUs "Rx-only".
- Rilonacept licenceUs "Arcalyst".
- Rilonacept pregnancyUs "C".
- Rilonacept routesOfAdministration "Subcutaneous".
- Rilonacept unii "8".
- Rilonacept verifiedfields "changed".
- Rilonacept verifiedrevid "464382495".
- Rilonacept subject Category:Engineered_proteins.
- Rilonacept subject Category:Immunosuppressants.
- Rilonacept type Abstraction100002137.
- Rilonacept type Chemical114806838.
- Rilonacept type Compound114818238.
- Rilonacept type EngineeredProteins.
- Rilonacept type Macromolecule114944888.
- Rilonacept type Material114580897.
- Rilonacept type Matter100020827.
- Rilonacept type Molecule114682133.
- Rilonacept type OrganicCompound114727670.
- Rilonacept type Part113809207.
- Rilonacept type PhysicalEntity100001930.
- Rilonacept type Protein114728724.
- Rilonacept type Relation100031921.
- Rilonacept type Substance100019613.
- Rilonacept type Thing100002452.
- Rilonacept type Unit109465459.
- Rilonacept type Drug.
- Rilonacept type DrugProduct.
- Rilonacept type FunctionalSubstance.
- Rilonacept comment "Rilonacept, also known as IL-1 Trap (marketed by Regeneron Pharmaceuticals under the trade name Arcalyst), is an interleukin 1 inhibitor.Rilonacept is a dimeric fusion protein consisting of the ligand-binding domains of the extracellular portions of the human interleukin-1 receptor component (IL-1R1) and IL-1 receptor accessory protein (IL-1RAcP) linked in-line to the fragment-crystallizable portion (Fc region) of human IgG1 that binds and neutralizes IL-1.Rilonacept was given an "Orphan Drug" status by the United States Food and Drug Administration and is used for the treatment of cryopyrin-associated periodic syndromes (CAPS), including familial cold autoinflammatory syndrome, Muckle-Wells syndrome and neonatal onset multisystem inflammatory disease(not approved in the U.S. ".
- Rilonacept label "Rilonacept".
- Rilonacept label "Rilonacept".
- Rilonacept sameAs Rilonacept.
- Rilonacept sameAs m.03wghqq.
- Rilonacept sameAs Q7334300.
- Rilonacept sameAs Q7334300.
- Rilonacept sameAs Rilonacept.
- Rilonacept wasDerivedFrom Rilonacept?oldid=592940611.
- Rilonacept isPrimaryTopicOf Rilonacept.