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- Rolofylline abstract "Rolofylline (KW-3902) is an experimental diuretic which acts as a selective adenosine A1 receptor antagonist. It was discovered at NovaCardia, Inc. which was purchased by Merck & Co., Inc. in 2007.Development of rolofylline was terminated on September 1, 2009, after the results of a large clinical trial (PROTECT) showed the drug to be no better than placebo for patients with acute heart failure. Participants given rolofylline did show some improvement in shortness of breath, but the drug did not prevent kidney damage or have any significant effect on overall treatment success. Rolofylline was also associated with a higher incidence of seizures and stroke.".
- Rolofylline atcPrefix "C03".
- Rolofylline atcSuffix "BD".
- Rolofylline casNumber "136199-02-5".
- Rolofylline fdaUniiCode "7805S5HIHX".
- Rolofylline iupacName "8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione".
- Rolofylline pubchem "64627".
- Rolofylline thumbnail Rolofylline.svg?width=300.
- Rolofylline wikiPageID "17253604".
- Rolofylline wikiPageRevisionID "592952031".
- Rolofylline atcPrefix "3.0".
- Rolofylline atcSuffix "BD".
- Rolofylline c "20".
- Rolofylline casNumber "136199".
- Rolofylline chemspiderid "58188".
- Rolofylline h "28".
- Rolofylline hasPhotoCollection Rolofylline.
- Rolofylline iupacName "8".
- Rolofylline legalUs "Rx-only".
- Rolofylline molecularWeight "356.46".
- Rolofylline n "4".
- Rolofylline o "2".
- Rolofylline pubchem "64627".
- Rolofylline unii "7805".
- Rolofylline width "220".
- Rolofylline subject Category:Adenosine_antagonists.
- Rolofylline subject Category:Diuretics.
- Rolofylline subject Category:Xanthines.
- Rolofylline type AdenosineAntagonists.
- Rolofylline type Adversary109773245.
- Rolofylline type CausalAgent100007347.
- Rolofylline type LivingThing100004258.
- Rolofylline type Object100002684.
- Rolofylline type Organism100004475.
- Rolofylline type Person100007846.
- Rolofylline type PhysicalEntity100001930.
- Rolofylline type Whole100003553.
- Rolofylline type YagoLegalActor.
- Rolofylline type YagoLegalActorGeo.
- Rolofylline type Drug.
- Rolofylline type DrugProduct.
- Rolofylline type FunctionalSubstance.
- Rolofylline comment "Rolofylline (KW-3902) is an experimental diuretic which acts as a selective adenosine A1 receptor antagonist. It was discovered at NovaCardia, Inc. which was purchased by Merck & Co., Inc. in 2007.Development of rolofylline was terminated on September 1, 2009, after the results of a large clinical trial (PROTECT) showed the drug to be no better than placebo for patients with acute heart failure.".
- Rolofylline label "Rolofilina".
- Rolofylline label "Rolofylline".
- Rolofylline sameAs ロロフィリン.
- Rolofylline sameAs Rolofilina.
- Rolofylline sameAs m.043shlw.
- Rolofylline sameAs Q7361410.
- Rolofylline sameAs Q7361410.
- Rolofylline sameAs Rolofylline.
- Rolofylline wasDerivedFrom Rolofylline?oldid=592952031.
- Rolofylline depiction Rolofylline.svg.
- Rolofylline isPrimaryTopicOf Rolofylline.