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- Ruppy abstract "Ruppy (short for Ruby Puppy) is the world's first transgenic dog. A cloned beagle, Ruppy and four other beagles produce a fluorescent protein that glows red upon excitation with ultraviolet light. Ruppy was created in 2009 by a group of scientists in South Korea, led by Byeong-Chun Lee. The dog was cloned using viral transfection of fibroblasts cells with an expresses the red fluorescent gene. The nucleus of the transfected fibroblast was then inserted into the enucleated oocyte of another dog, leading to generation of dog oocytes expressing the red fluorescent protein. These cloned embryos were then implanted into the uterus of a surrogate mother. It was hoped to use this procedure to investigate the effect of the hormone oestrogen on fertility. The ruppy puppy was then shipped to the north of Croatia where it was thoroughly examined by doctor Lisa Dajci who clarified that the puppy could in fact be classed in the dog species even though it had not been born 100 percent naturally it did still have all the characteristics of the species.".
- Ruppy wikiPageID "22553956".
- Ruppy wikiPageRevisionID "596939810".
- Ruppy hasPhotoCollection Ruppy.
- Ruppy subject Category:2009_animal_births.
- Ruppy subject Category:Cloned_dogs.
- Ruppy subject Category:Genetically_modified_organisms.
- Ruppy type Animal100015388.
- Ruppy type Canine102083346.
- Ruppy type Carnivore102075296.
- Ruppy type Chordate101466257.
- Ruppy type ClonedAnimals.
- Ruppy type ClonedDogs.
- Ruppy type Dog102084071.
- Ruppy type DomesticAnimal101317541.
- Ruppy type GeneticallyModifiedOrganisms.
- Ruppy type IndividualDogs.
- Ruppy type LivingThing100004258.
- Ruppy type Mammal101861778.
- Ruppy type Object100002684.
- Ruppy type Organism100004475.
- Ruppy type PhysicalEntity100001930.
- Ruppy type Placental101886756.
- Ruppy type Vertebrate101471682.
- Ruppy type Whole100003553.
- Ruppy comment "Ruppy (short for Ruby Puppy) is the world's first transgenic dog. A cloned beagle, Ruppy and four other beagles produce a fluorescent protein that glows red upon excitation with ultraviolet light. Ruppy was created in 2009 by a group of scientists in South Korea, led by Byeong-Chun Lee. The dog was cloned using viral transfection of fibroblasts cells with an expresses the red fluorescent gene.".
- Ruppy label "Ruppy".
- Ruppy sameAs m.05zk3nb.
- Ruppy sameAs Q7380439.
- Ruppy sameAs Q7380439.
- Ruppy sameAs Ruppy.
- Ruppy wasDerivedFrom Ruppy?oldid=596939810.
- Ruppy isPrimaryTopicOf Ruppy.