Matches in DBpedia 2014 for { <http://dbpedia.org/resource/SGN-CD33A> ?p ?o. }
Showing items 1 to 18 of
18
with 100 items per page.
- SGN-CD33A abstract "SGN-CD33A is an antibody-drug conjugate (ADC) directed to CD33 designed for the treatment of Acute myeloid leukemia. It consists of a humanized anti-CD33 mAb with 2 engineered cysteine residues. The payloads are pyrrolobenzodiazepine (PBD) dimers which are conjugated with a maleimidocaproyl valine-alanine dipeptide linker. PBD dimers exert their biological activity by covalent binding and interstrand cross-linking of DNA.The drug is currently in phase I clinical trials for Acute myeloid leukemia".
- SGN-CD33A atcPrefix "none".
- SGN-CD33A wikiPageID "41331931".
- SGN-CD33A wikiPageRevisionID "585559948".
- SGN-CD33A atcPrefix "none".
- SGN-CD33A source "zu/o".
- SGN-CD33A target CD33.
- SGN-CD33A type "mab".
- SGN-CD33A subject Category:Monoclonal_antibodies.
- SGN-CD33A type Drug.
- SGN-CD33A type FunctionalSubstance.
- SGN-CD33A comment "SGN-CD33A is an antibody-drug conjugate (ADC) directed to CD33 designed for the treatment of Acute myeloid leukemia. It consists of a humanized anti-CD33 mAb with 2 engineered cysteine residues. The payloads are pyrrolobenzodiazepine (PBD) dimers which are conjugated with a maleimidocaproyl valine-alanine dipeptide linker. PBD dimers exert their biological activity by covalent binding and interstrand cross-linking of DNA.The drug is currently in phase I clinical trials for Acute myeloid leukemia".
- SGN-CD33A label "SGN-CD33A".
- SGN-CD33A sameAs m.0zmyw2q.
- SGN-CD33A sameAs Q17044502.
- SGN-CD33A sameAs Q17044502.
- SGN-CD33A wasDerivedFrom SGN-CD33A?oldid=585559948.
- SGN-CD33A isPrimaryTopicOf SGN-CD33A.