Matches in DBpedia 2014 for { <http://dbpedia.org/resource/SLC22A8> ?p ?o. }
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- SLC22A8 abstract "Solute carrier family 22 member 8 is a protein that in humans is encoded by the SLC22A8 gene. This protein is also called organic anion transporter 3 (OAT3). It is involved in the transport and excretion of organic ions some of which are drugs (e.g., penicillin G (benzylpenicillin), methotrexate (MTX), indomethacin (an NSAID), ciprofloxacin (a carboxyfluoroquinolone), and some of which are pure toxicants. SLC22A8 (OAT3) is indirectly dependent on the inward sodium gradient, which is a driving force for reentry of dicarboxylates into the cytosol. Dicarboxylates, such as alpha-ketoglutarate generated within the cell, or recycled from the extracellular space, are used as exchange substrates to fuel the influx of organic anions against their concentration gradient. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of renal proximal tubule cells.".
- SLC22A8 entrezgene "9376".
- SLC22A8 wikiPageID "14879142".
- SLC22A8 wikiPageRevisionID "500870559".
- SLC22A8 hasPhotoCollection SLC22A8.
- SLC22A8 requireManualInspection "no".
- SLC22A8 summaryText "This protein is also called organic anion transporter 3 . It is involved in the transport and excretion of organic ions some of which are drugs".
- SLC22A8 updateCitations "yes".
- SLC22A8 updatePage "yes".
- SLC22A8 updateProteinBox "yes".
- SLC22A8 updateSummary "yes".
- SLC22A8 type Biomolecule.
- SLC22A8 type Protein.
- SLC22A8 type BiologicalObject.
- SLC22A8 comment "Solute carrier family 22 member 8 is a protein that in humans is encoded by the SLC22A8 gene. This protein is also called organic anion transporter 3 (OAT3). It is involved in the transport and excretion of organic ions some of which are drugs (e.g., penicillin G (benzylpenicillin), methotrexate (MTX), indomethacin (an NSAID), ciprofloxacin (a carboxyfluoroquinolone), and some of which are pure toxicants.".
- SLC22A8 label "SLC22A8".
- SLC22A8 sameAs m.03h025r.
- SLC22A8 sameAs Q15997149.
- SLC22A8 sameAs Q15997149.
- SLC22A8 sameAs 747.
- SLC22A8 wasDerivedFrom SLC22A8?oldid=500870559.
- SLC22A8 isPrimaryTopicOf SLC22A8.