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- SNX13 abstract "Sorting nexin-13 is a protein that in humans is encoded by the SNX13 gene.This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.".
- SNX13 entrezgene "23161".
- SNX13 wikiPageID "15229380".
- SNX13 wikiPageRevisionID "593066558".
- SNX13 hasPhotoCollection SNX13.
- SNX13 requireManualInspection "no".
- SNX13 summaryText "This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin family and the regulator of G protein signaling family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha, accelerates its GTP hydrolysis, and attenuates G alpha-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.".
- SNX13 updateCitations "yes".
- SNX13 updatePage "yes".
- SNX13 updateProteinBox "yes".
- SNX13 updateSummary "yes".
- SNX13 type Biomolecule.
- SNX13 type Protein.
- SNX13 type BiologicalObject.
- SNX13 comment "Sorting nexin-13 is a protein that in humans is encoded by the SNX13 gene.This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking.".
- SNX13 label "SNX13".
- SNX13 sameAs m.03hmnsy.
- SNX13 sameAs Q7391922.
- SNX13 sameAs Q7391922.
- SNX13 wasDerivedFrom SNX13?oldid=593066558.
- SNX13 isPrimaryTopicOf SNX13.