Matches in DBpedia 2014 for { <http://dbpedia.org/resource/SPAG6> ?p ?o. }
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- SPAG6 abstract "Sperm-associated antigen 6 is a protein that in humans is encoded by the SPAG6 gene.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.".
- SPAG6 entrezgene "9576".
- SPAG6 wikiPageID "14879204".
- SPAG6 wikiPageRevisionID "593079363".
- SPAG6 hasPhotoCollection SPAG6.
- SPAG6 requireManualInspection "no".
- SPAG6 summaryText "The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.".
- SPAG6 updateCitations "yes".
- SPAG6 updatePage "yes".
- SPAG6 updateProteinBox "yes".
- SPAG6 updateSummary "yes".
- SPAG6 type Biomolecule.
- SPAG6 type Protein.
- SPAG6 type BiologicalObject.
- SPAG6 comment "Sperm-associated antigen 6 is a protein that in humans is encoded by the SPAG6 gene.The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens.".
- SPAG6 label "SPAG6".
- SPAG6 sameAs m.03h0298.
- SPAG6 sameAs Q7392434.
- SPAG6 sameAs Q7392434.
- SPAG6 wasDerivedFrom SPAG6?oldid=593079363.
- SPAG6 isPrimaryTopicOf SPAG6.