Matches in DBpedia 2014 for { <http://dbpedia.org/resource/SPEN> ?p ?o. }
Showing items 1 to 23 of
23
with 100 items per page.
- SPEN abstract "Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.".
- SPEN entrezgene "23013".
- SPEN wikiPageID "14800968".
- SPEN wikiPageRevisionID "593081706".
- SPEN hasPhotoCollection SPEN.
- SPEN requireManualInspection "no".
- SPEN summaryText "This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.".
- SPEN updateCitations "yes".
- SPEN updatePage "yes".
- SPEN updateProteinBox "yes".
- SPEN updateSummary "yes".
- SPEN type Biomolecule.
- SPEN type Protein.
- SPEN type BiologicalObject.
- SPEN comment "Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins.".
- SPEN label "SPEN".
- SPEN label "SPEN".
- SPEN sameAs SPEN.
- SPEN sameAs m.03gygbp.
- SPEN sameAs Q7392537.
- SPEN sameAs Q7392537.
- SPEN wasDerivedFrom SPEN?oldid=593081706.
- SPEN isPrimaryTopicOf SPEN.