Matches in DBpedia 2014 for { <http://dbpedia.org/resource/STAT2> ?p ?o. }
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- STAT2 abstract "Signal transducer and activator of transcription 2 is a protein that in humans is encoded by the STAT2 gene.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.".
- STAT2 entrezgene "6773".
- STAT2 wikiPageID "11935113".
- STAT2 wikiPageRevisionID "593092587".
- STAT2 hasPhotoCollection STAT2.
- STAT2 requireManualInspection "no".
- STAT2 summaryText "The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon , this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 , in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.".
- STAT2 updateCitations "yes".
- STAT2 updatePage "yes".
- STAT2 updateProteinBox "yes".
- STAT2 updateSummary "yes".
- STAT2 subject Category:Gene_expression.
- STAT2 subject Category:Immune_system.
- STAT2 subject Category:Proteins.
- STAT2 subject Category:Signal_transduction.
- STAT2 subject Category:Transcription_factors.
- STAT2 type Biomolecule.
- STAT2 type Protein.
- STAT2 type BiologicalObject.
- STAT2 comment "Signal transducer and activator of transcription 2 is a protein that in humans is encoded by the STAT2 gene.The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.".
- STAT2 label "STAT2".
- STAT2 label "STAT2".
- STAT2 sameAs STAT-2.
- STAT2 sameAs m.02rypxp.
- STAT2 sameAs Q14475502.
- STAT2 sameAs Q14475502.
- STAT2 wasDerivedFrom STAT2?oldid=593092587.
- STAT2 isPrimaryTopicOf STAT2.