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- STK24 abstract "Serine/threonine-protein kinase 24 is an enzyme that in humans is encoded by the STK24 gene.The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000).[supplied by OMIM]".
- STK24 entrezgene "8428".
- STK24 wikiPageID "15065925".
- STK24 wikiPageRevisionID "602181523".
- STK24 hasPhotoCollection STK24.
- STK24 requireManualInspection "no".
- STK24 summaryText "The yeast 'Sterile 20' gene functions upstream of the mitogen-activated protein kinase cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 -binding domain. In contrast, members of the GCK subfamily , also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases .[supplied by OMIM]".
- STK24 updateCitations "yes".
- STK24 updatePage "yes".
- STK24 updateProteinBox "yes".
- STK24 updateSummary "yes".
- STK24 subject Category:Biology_of_bipolar_disorder.
- STK24 type Biomolecule.
- STK24 type Protein.
- STK24 type BiologicalObject.
- STK24 comment "Serine/threonine-protein kinase 24 is an enzyme that in humans is encoded by the STK24 gene.The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain.".
- STK24 label "STK24".
- STK24 sameAs m.03hgc4t.
- STK24 sameAs Q7394757.
- STK24 sameAs Q7394757.
- STK24 wasDerivedFrom STK24?oldid=602181523.
- STK24 isPrimaryTopicOf STK24.