Matches in DBpedia 2014 for { <http://dbpedia.org/resource/SUMF1> ?p ?o. }
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- SUMF1 abstract "Sulfatase-modifying factor 1 is an enzyme that in humans is encoded by the SUMF1 gene.Sulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine (FGly), the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme (FGE), in the endoplasmic reticulum (ER). The genetic defect of FGly formation caused by mutations in the SUMF1 gene results in multiple sulfatase deficiency (MSD; MIM 272200), a lysosomal storage disorder (Roeser et al., 2006).[supplied by OMIM]".
- SUMF1 entrezgene "285362".
- SUMF1 wikiPageID "14877673".
- SUMF1 wikiPageRevisionID "593107453".
- SUMF1 hasPhotoCollection SUMF1.
- SUMF1 requireManualInspection "no".
- SUMF1 summaryText "Sulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine , the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme , in the endoplasmic reticulum . The genetic defect of FGly formation caused by mutations in the SUMF1 gene results in multiple sulfatase deficiency , a lysosomal storage disorder .[supplied by OMIM]".
- SUMF1 updateCitations "yes".
- SUMF1 updatePage "yes".
- SUMF1 updateProteinBox "yes".
- SUMF1 updateSummary "yes".
- SUMF1 type Biomolecule.
- SUMF1 type Protein.
- SUMF1 type BiologicalObject.
- SUMF1 comment "Sulfatase-modifying factor 1 is an enzyme that in humans is encoded by the SUMF1 gene.Sulfatases catalyze the hydrolysis of sulfate esters such as glycosaminoglycans, sulfolipids, and steroid sulfates. C-alpha-formylglycine (FGly), the catalytic residue in the active site of eukaryotic sulfatases, is posttranslationally generated from a cysteine by SUMF1, the FGly-generating enzyme (FGE), in the endoplasmic reticulum (ER).".
- SUMF1 label "SUMF1".
- SUMF1 sameAs m.03g__1x.
- SUMF1 sameAs Q7394988.
- SUMF1 sameAs Q7394988.
- SUMF1 sameAs SUMF1.
- SUMF1 wasDerivedFrom SUMF1?oldid=593107453.
- SUMF1 isPrimaryTopicOf SUMF1.