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- SUMF2 abstract "Sulfatase-modifying factor 2 is an enzyme that in humans is encoded by the SUMF2 gene.The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.".
- SUMF2 entrezgene "25870".
- SUMF2 wikiPageID "14817549".
- SUMF2 wikiPageRevisionID "601784894".
- SUMF2 hasPhotoCollection SUMF2.
- SUMF2 requireManualInspection "no".
- SUMF2 summaryText "The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine . The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.".
- SUMF2 updateCitations "yes".
- SUMF2 updatePage "yes".
- SUMF2 updateProteinBox "yes".
- SUMF2 updateSummary "yes".
- SUMF2 type Biomolecule.
- SUMF2 type Protein.
- SUMF2 type BiologicalObject.
- SUMF2 comment "Sulfatase-modifying factor 2 is an enzyme that in humans is encoded by the SUMF2 gene.The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum.".
- SUMF2 label "SUMF2".
- SUMF2 sameAs m.03gyzr3.
- SUMF2 sameAs Q7394991.
- SUMF2 sameAs Q7394991.
- SUMF2 sameAs 2212.
- SUMF2 wasDerivedFrom SUMF2?oldid=601784894.
- SUMF2 isPrimaryTopicOf SUMF2.