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- SYN3 abstract "Synapsin-3 is a protein that in humans is encoded by the SYN3 gene.This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in six transcript variants; however, only two variants have been fully described.".
- SYN3 entrezgene "8224".
- SYN3 wikiPageID "14881905".
- SYN3 wikiPageRevisionID "593117554".
- SYN3 hasPhotoCollection SYN3.
- SYN3 requireManualInspection "no".
- SYN3 summaryText "This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in six transcript variants; however, only two variants have been fully described.".
- SYN3 updateCitations "yes".
- SYN3 updatePage "yes".
- SYN3 updateProteinBox "yes".
- SYN3 updateSummary "yes".
- SYN3 subject Category:Biology_of_bipolar_disorder.
- SYN3 type Biomolecule.
- SYN3 type Protein.
- SYN3 type BiologicalObject.
- SYN3 comment "Synapsin-3 is a protein that in humans is encoded by the SYN3 gene.This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.".
- SYN3 label "SYN3".
- SYN3 sameAs m.03h0995.
- SYN3 sameAs Q7395258.
- SYN3 sameAs Q7395258.
- SYN3 wasDerivedFrom SYN3?oldid=593117554.
- SYN3 isPrimaryTopicOf SYN3.