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- Schild_regression abstract "Schild regression analysis, named for Heinz Otto Schild, is a useful tool for studying the effects of agonists and antagonists on the cellular response caused by the receptor or on ligand-receptor binding.Using a dose-response curve or an equivalent curve with concentration and binding %, it is possible to determine the dose ratio, this is a measure of the potency of a drug; it is obtained by dividing the increased equilibrium constant due to drug inhibition by the equilibrium constant without the drug. A Schild plot is a double logarithmic plot, typically Log(dr-1) as the ordinate and Log[B] as the abscissa. This is because a competitive drug B will have a linear plot with the .These experiments must be carried out on a very wide range (therefore the logarithmic scale) as the mechanisms differ over a large scale, such as at high concentration of drug.".
- Schild_regression thumbnail Schild_regression_bindings.jpg?width=300.
- Schild_regression wikiPageExternalLink schild.htm.
- Schild_regression wikiPageID "9374505".
- Schild_regression wikiPageRevisionID "593008718".
- Schild_regression hasPhotoCollection Schild_regression.
- Schild_regression subject Category:Biochemistry_methods.
- Schild_regression subject Category:Pharmacology.
- Schild_regression type Ability105616246.
- Schild_regression type Abstraction100002137.
- Schild_regression type BiochemistryMethods.
- Schild_regression type Cognition100023271.
- Schild_regression type Know-how105616786.
- Schild_regression type Method105660268.
- Schild_regression type PsychologicalFeature100023100.
- Schild_regression comment "Schild regression analysis, named for Heinz Otto Schild, is a useful tool for studying the effects of agonists and antagonists on the cellular response caused by the receptor or on ligand-receptor binding.Using a dose-response curve or an equivalent curve with concentration and binding %, it is possible to determine the dose ratio, this is a measure of the potency of a drug; it is obtained by dividing the increased equilibrium constant due to drug inhibition by the equilibrium constant without the drug. ".
- Schild_regression label "Schild regression".
- Schild_regression label "Schild-Plot".
- Schild_regression sameAs Schild-Plot.
- Schild_regression sameAs m.0286d1y.
- Schild_regression sameAs Q2235423.
- Schild_regression sameAs Q2235423.
- Schild_regression sameAs Schild_regression.
- Schild_regression wasDerivedFrom Schild_regression?oldid=593008718.
- Schild_regression depiction Schild_regression_bindings.jpg.
- Schild_regression isPrimaryTopicOf Schild_regression.
