Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Secnidazole> ?p ?o. }
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- Secnidazole abstract "Secnidazole (trade names Flagentyl, Sindose, Secnil) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae.Secnidazole is structurally related to the commonly used 5-nitroimidazoles metronidazole and tinidazole. These drugs share a common spectrum of activity against anaerobic micro-organisms and they appear particularly effective in the treatment of amoebiasis, giardiasis, trichomoniasis and bacterial vaginosis. Secnidazole is rapidly and completely absorbed after oral administration and has a longer terminal elimination half-life (approximately 17 to 29 hours) than commonly used drugs in this class. In patients with intestinal amoebiasis or giardiasis, clinical or parasistological cure rates of 80 to 100% are achieved after treatment with a single dose of secnidazole 2 g (30 mg/kg in children), similar to the response rates achieved with multiple dosage regimens of metronidazole or tinidazole. Patients with hepatic amoebiasis appears to respond well to 5- to 7-day therapy with secnidazole, but the efficacy of this drug regimen requires further evaluation in larger numbers of patients. After administration of a single dose of secnidazole, parasitological eradication was achieved in approximately 92 to 100% of patients with urogenital trichomoniasis. Patients with bacteria vaginosis respond at least as well to a single dose of secnidazole as to single-dose tinidazole, or single- or 7-day treatment with metronidazole; clinical improvement and/or microbiological evidence of cure was attained in approximately 59 to 96% of patients. In the clinical trials reviewed, secnidazole was well tolerated; most adverse events were gastrointestinal in nature and did not require treatment intervention or withdrawal from therapy.In summary, available evidence suggests that secnidazole is as efficacious as other 5-nitroimidazole drugs in the treatment of protozoal infections and bacterial vaginosis. The convenience and ease of administration associated with single-dose therapy, combined with a good tolerability profile, make secnidazole a suitable option to other single-dose treatments and an attractive alternative to multiple dosage regimens with other drugs in this class.".
- Secnidazole atcPrefix "P01".
- Secnidazole atcSuffix "AB07".
- Secnidazole casNumber "3366-95-8".
- Secnidazole fdaUniiCode "R3459K699K".
- Secnidazole iupacName "1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol".
- Secnidazole pubchem "71815".
- Secnidazole thumbnail Secnidazole.svg?width=300.
- Secnidazole wikiPageExternalLink A-zglcyxzz200604008.html.
- Secnidazole wikiPageExternalLink Abstract.aspx?A=zgkgrhlzz200603004.
- Secnidazole wikiPageID "17327236".
- Secnidazole wikiPageRevisionID "586875703".
- Secnidazole atcPrefix "P01".
- Secnidazole atcSuffix "AB07".
- Secnidazole c "7".
- Secnidazole casNumber "3366".
- Secnidazole chembl "498847".
- Secnidazole chemspiderid "64839".
- Secnidazole h "11".
- Secnidazole hasPhotoCollection Secnidazole.
- Secnidazole inchi "1".
- Secnidazole inchikey "KPQZUUQMTUIKBP-UHFFFAOYAM".
- Secnidazole iupacName "1".
- Secnidazole kegg "D07353".
- Secnidazole molecularWeight "185.18".
- Secnidazole n "3".
- Secnidazole o "3".
- Secnidazole pubchem "71815".
- Secnidazole routesOfAdministration "Oral".
- Secnidazole smiles "[O-][N+]c1cncC".
- Secnidazole stdinchi "1".
- Secnidazole stdinchikey "KPQZUUQMTUIKBP-UHFFFAOYSA-N".
- Secnidazole synonyms "PM 185184, RP 14539".
- Secnidazole unii "R3459K699K".
- Secnidazole verifiedrevid "464388214".
- Secnidazole subject Category:Antiprotozoal_agents.
- Secnidazole subject Category:Nitroimidazole_antibiotics.
- Secnidazole type Agent109190918.
- Secnidazole type Agent114778436.
- Secnidazole type Antibacterial102716205.
- Secnidazole type Antibiotic102716866.
- Secnidazole type AntiprotozoalAgents.
- Secnidazole type CausalAgent100007347.
- Secnidazole type Drug103247620.
- Secnidazole type Matter100020827.
- Secnidazole type Medicine103740161.
- Secnidazole type NitroimidazoleAntibiotics.
- Secnidazole type PhysicalEntity100001930.
- Secnidazole type Substance100020090.
- Secnidazole type Drug.
- Secnidazole type DrugProduct.
- Secnidazole type FunctionalSubstance.
- Secnidazole comment "Secnidazole (trade names Flagentyl, Sindose, Secnil) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae.Secnidazole is structurally related to the commonly used 5-nitroimidazoles metronidazole and tinidazole.".
- Secnidazole label "Secnidazol".
- Secnidazole label "Secnidazole".
- Secnidazole label "Секнидазол".
- Secnidazole sameAs Secnidazol.
- Secnidazole sameAs m.043ld1k.
- Secnidazole sameAs Q4413249.
- Secnidazole sameAs Q4413249.
- Secnidazole sameAs Secnidazole.
- Secnidazole wasDerivedFrom Secnidazole?oldid=586875703.
- Secnidazole depiction Secnidazole.svg.
- Secnidazole isPrimaryTopicOf Secnidazole.
