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- Sedimentation_coefficient abstract "The sedimentation coefficient s of a particle is used to characterize its behaviour in sedimentation processes, notably centrifugation. It is defined as the ratio of a particle's sedimentation velocity to the acceleration that is applied to it (causing the sedimentation). The sedimentation speed (in ms−1) is also known as the terminal velocity. It is constant because the force applied to a particle by gravity or by a centrifuge (measuring typically in multiples of tens of thousands of gravities in an ultracentrifuge) is cancelled by the viscous resistance of the medium (normally water) through which the particle is moving. The applied acceleration a (in ms−2) can be either the gravitational acceleration g, or more commonly the centrifugal acceleration . In the latter case, is the angular velocity of the rotor and r is the distance of a particle to the rotor axis (radius).The viscous resistance is given by the Stokes' law: 6πηr0v where η is the viscosity of the medium, r0 is the radius of the particle and v is the velocity of the particle. This law applies only for large spheres in an infinite sea of the fluid.The centrifugal force is given by the familiar equation: mrω2. Here r is the distance of the particle from the axis of rotation. When the two forces (viscous force and the centrifugal force) balance (they are oppositely directed), the particle moves with constant velocity called the terminal velocity. Hence the terminal velocity is given by the following equation. Rearranging this equation we get the final formula: The sedimentation coefficient has the dimensions of a unit of time and is expressed in svedbergs. One svedberg is defined as exactly 10−13 s. Essentially the sedimentation coefficient serves to normalize the sedimentation rate of a particle by the acceleration applied to it. The resulting value is no longer dependent on the acceleration, but depends only on the properties of the particle and the medium in which it is suspended. Sedimentation coefficients quoted in literature usually pertain to sedimentation in water at 20°C.Bigger particles sediment faster and have higher sedimentation coefficients (svedberg, or S values). Sedimentation coefficients are, however, not additive. Sedimentation rate does not depend only on the mass or volume of a particle, and when two particles bind together there is inevitably a loss of surface area. Thus when measured separately they will have svedberg values that may not add up to that of the bound particle. This is notably the case with the ribosome. Ribosomes are most often identified by their sedimentation coefficient. For instance, the 70 S ribosome that comes from bacteria has actually a sedimentation coefficient of 70 svedberg, although it is composed of a 50 S subunit and a 30 S subunit.".
- Sedimentation_coefficient wikiPageExternalLink intro3.html.
- Sedimentation_coefficient wikiPageExternalLink index-1.html.
- Sedimentation_coefficient wikiPageExternalLink sedimentation_velocity.htm.
- Sedimentation_coefficient wikiPageExternalLink Vel_data_analysis.htm.
- Sedimentation_coefficient wikiPageExternalLink PMC2373601.
- Sedimentation_coefficient wikiPageID "3402094".
- Sedimentation_coefficient wikiPageRevisionID "604452973".
- Sedimentation_coefficient hasPhotoCollection Sedimentation_coefficient.
- Sedimentation_coefficient subject Category:Laboratory_techniques.
- Sedimentation_coefficient subject Category:Unit_operations.
- Sedimentation_coefficient type Ability105616246.
- Sedimentation_coefficient type Abstraction100002137.
- Sedimentation_coefficient type Action114006945.
- Sedimentation_coefficient type Attribute100024264.
- Sedimentation_coefficient type Cognition100023271.
- Sedimentation_coefficient type Know-how105616786.
- Sedimentation_coefficient type LaboratoryTechniques.
- Sedimentation_coefficient type Method105660268.
- Sedimentation_coefficient type Operation114008806.
- Sedimentation_coefficient type PsychologicalFeature100023100.
- Sedimentation_coefficient type State100024720.
- Sedimentation_coefficient type Technique105665146.
- Sedimentation_coefficient type UnitOperations.
- Sedimentation_coefficient comment "The sedimentation coefficient s of a particle is used to characterize its behaviour in sedimentation processes, notably centrifugation. It is defined as the ratio of a particle's sedimentation velocity to the acceleration that is applied to it (causing the sedimentation). The sedimentation speed (in ms−1) is also known as the terminal velocity.".
- Sedimentation_coefficient label "Coefficiente di sedimentazione".
- Sedimentation_coefficient label "Coeficiente de sedimentación".
- Sedimentation_coefficient label "Sedimentation coefficient".
- Sedimentation_coefficient label "Sedimentationskoeffizient".
- Sedimentation_coefficient label "沈降係数".
- Sedimentation_coefficient sameAs Sedimentationskoeffizient.
- Sedimentation_coefficient sameAs Coeficiente_de_sedimentación.
- Sedimentation_coefficient sameAs Coefficiente_di_sedimentazione.
- Sedimentation_coefficient sameAs 沈降係数.
- Sedimentation_coefficient sameAs m.04lcny9.
- Sedimentation_coefficient sameAs Q3132613.
- Sedimentation_coefficient sameAs Q3132613.
- Sedimentation_coefficient sameAs Sedimentation_coefficient.
- Sedimentation_coefficient wasDerivedFrom Sedimentation_coefficient?oldid=604452973.
- Sedimentation_coefficient isPrimaryTopicOf Sedimentation_coefficient.