Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Semaxanib> ?p ?o. }
Showing items 1 to 54 of
54
with 100 items per page.
- Semaxanib abstract "Semaxanib (SU5416) is a tyrosine-kinase inhibitor drug designed by SUGEN as a cancer therapeutic. It is an experimental stage drug, not licensed for use on human patients outside of clinical trials.Semaxanib is a potent and selective synthetic inhibitor of the Flk-1/KDR vascular endothelial growth factor (VEGF) receptor tyrosine kinase. It targets the VEGF pathway, and both in vivo and in vitro studies have demonstrated antiangiogenic potential.On February 2002, Pharmacia, the then parent of Sugen, prematurely ended Phase III clinical trials of Semaxinib in the treatment of advanced colorectal cancer due to discouraging results. Other studies, at earlier phases, have since been conducted. However, due to the prospect of next-generation tyrosine kinase inhibitors and the ineffaciousness of semaxanib in clinic trials, further development of the drug has been discontinued. A related compound, SU11248 was further developed by Sugen, and then by Pfizer and was FDA-approved as Sunitinib (Sutent) for treatment of renal carcinoma in January 2006.".
- Semaxanib atcPrefix "none".
- Semaxanib casNumber "194413-58-6".
- Semaxanib fdaUniiCode "71IA9S35AJ".
- Semaxanib iupacName "(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one".
- Semaxanib pubchem "5329098".
- Semaxanib thumbnail Semaxanib.svg?width=300.
- Semaxanib wikiPageID "9751443".
- Semaxanib wikiPageRevisionID "572046325".
- Semaxanib atcPrefix "none".
- Semaxanib c "15".
- Semaxanib casNumber "194413".
- Semaxanib chembl "276711".
- Semaxanib chemspiderid "4486260".
- Semaxanib h "14".
- Semaxanib hasPhotoCollection Semaxanib.
- Semaxanib inchi "1".
- Semaxanib inchikey "WUWDLXZGHZSWQZ-WQLSENKSBZ".
- Semaxanib iupacName "-3".
- Semaxanib molecularWeight "238.285".
- Semaxanib n "2".
- Semaxanib o "1".
- Semaxanib pubchem "5329098".
- Semaxanib smiles "O=C2C=C/c3cC".
- Semaxanib stdinchi "1".
- Semaxanib stdinchikey "WUWDLXZGHZSWQZ-WQLSENKSSA-N".
- Semaxanib unii "71".
- Semaxanib verifiedfields "changed".
- Semaxanib verifiedrevid "464389051".
- Semaxanib subject Category:Indolines.
- Semaxanib subject Category:Lactams.
- Semaxanib subject Category:Pyrroles.
- Semaxanib subject Category:Receptor_tyrosine_kinase_inhibitors.
- Semaxanib type Agent114778436.
- Semaxanib type CausalAgent100007347.
- Semaxanib type Drug103247620.
- Semaxanib type Matter100020827.
- Semaxanib type Medicine103740161.
- Semaxanib type PhysicalEntity100001930.
- Semaxanib type ReceptorTyrosineKinaseInhibitors.
- Semaxanib type Substance100020090.
- Semaxanib type TyrosineKinaseInhibitor104506005.
- Semaxanib type Drug.
- Semaxanib type DrugProduct.
- Semaxanib type FunctionalSubstance.
- Semaxanib comment "Semaxanib (SU5416) is a tyrosine-kinase inhibitor drug designed by SUGEN as a cancer therapeutic. It is an experimental stage drug, not licensed for use on human patients outside of clinical trials.Semaxanib is a potent and selective synthetic inhibitor of the Flk-1/KDR vascular endothelial growth factor (VEGF) receptor tyrosine kinase.".
- Semaxanib label "Semaxanib".
- Semaxanib sameAs m.02pr1xh.
- Semaxanib sameAs Q7449140.
- Semaxanib sameAs Q7449140.
- Semaxanib sameAs Semaxanib.
- Semaxanib wasDerivedFrom Semaxanib?oldid=572046325.
- Semaxanib depiction Semaxanib.svg.
- Semaxanib isPrimaryTopicOf Semaxanib.
