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- Sequencing_by_hybridization abstract "Sequencing by hybridization is a class of methods for determining the order in which nucleotides occur on a strand of DNA. Typically used for looking for small changes relative to a known DNA sequence.The binding of one strand of DNA to its complementary strand in the DNA double-helix (aka hybridization) is sensitive to even single-base mismatches when the hybrid region is short or if specialized mismatch detection proteins are present. This is exploited in a variety of ways, most notable via DNA chips or microarrays with thousands to billions of synthetic oligonucleotides found in a genome of interest plus many known variations or even all possible single-base variations. The type of sequencing by hybridization described above has largely been displaced by other methods, including sequencing by synthesis, and sequencing by ligation (as well as pore-based methods). However hybridization of oligonucleotides is still used in some sequencing schemes, including hybridization-assisted pore-based sequencing, and reversible hybridization.".
- Sequencing_by_hybridization wikiPageID "6433008".
- Sequencing_by_hybridization wikiPageRevisionID "593016002".
- Sequencing_by_hybridization hasPhotoCollection Sequencing_by_hybridization.
- Sequencing_by_hybridization subject Category:DNA_sequencing.
- Sequencing_by_hybridization subject Category:Laboratory_techniques.
- Sequencing_by_hybridization type Ability105616246.
- Sequencing_by_hybridization type Abstraction100002137.
- Sequencing_by_hybridization type Cognition100023271.
- Sequencing_by_hybridization type Know-how105616786.
- Sequencing_by_hybridization type LaboratoryTechniques.
- Sequencing_by_hybridization type Method105660268.
- Sequencing_by_hybridization type PsychologicalFeature100023100.
- Sequencing_by_hybridization type Technique105665146.
- Sequencing_by_hybridization comment "Sequencing by hybridization is a class of methods for determining the order in which nucleotides occur on a strand of DNA. Typically used for looking for small changes relative to a known DNA sequence.The binding of one strand of DNA to its complementary strand in the DNA double-helix (aka hybridization) is sensitive to even single-base mismatches when the hybrid region is short or if specialized mismatch detection proteins are present.".
- Sequencing_by_hybridization label "Sequencing by hybridization".
- Sequencing_by_hybridization sameAs m.0g54w0.
- Sequencing_by_hybridization sameAs Q7452482.
- Sequencing_by_hybridization sameAs Q7452482.
- Sequencing_by_hybridization sameAs Sequencing_by_hybridization.
- Sequencing_by_hybridization wasDerivedFrom Sequencing_by_hybridization?oldid=593016002.
- Sequencing_by_hybridization isPrimaryTopicOf Sequencing_by_hybridization.