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- Signal_recognition_particle_RNA abstract "The signal recognition particle RNA, also known as 7SL, 6S, ffs, or 4.5S RNA, is the RNA component of the signal recognition particle (SRP) ribonucleoprotein complex. SRP is a universally conserved ribonucleoprotein that directs the traffic of proteins within the cell and allows them to be secreted. The SRP RNA, together with one or more SRP proteins contributes to the binding and release of the signal peptide. The RNA and protein components of this complex are highly conserved but do vary between the different kingdoms of life.The common SINE family Alu probably originated from a 7SL RNA gene after deletion of a central sequence.The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures.In most bacteria, the SRP consists of an RNA molecule (4.5S) and the Ffh protein (a homologue of the eukaryotic SRP54 protein). Some Gram-positive bacteria (e.g. Bacillus subtilis) have a longer eukaryote-like SRP RNA that includes an Alu domain.In eukaryotes and archaea, eight helical elements fold into the Alu and S domains, separated by a long linker region. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition. The SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54. binding The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats.".
- Signal_recognition_particle_RNA entrezgene "6029".
- Signal_recognition_particle_RNA symbol "SRP RNA".
- Signal_recognition_particle_RNA thumbnail HomosapiSRPRNA-2d.png?width=300.
- Signal_recognition_particle_RNA wikiPageExternalLink RF00017.
- Signal_recognition_particle_RNA wikiPageExternalLink RF00169.
- Signal_recognition_particle_RNA wikiPageExternalLink RF01502.
- Signal_recognition_particle_RNA wikiPageExternalLink RF01854.
- Signal_recognition_particle_RNA wikiPageExternalLink RF01855.
- Signal_recognition_particle_RNA wikiPageExternalLink RF01856.
- Signal_recognition_particle_RNA wikiPageExternalLink RF01857.
- Signal_recognition_particle_RNA wikiPageExternalLink SRPDB.html.
- Signal_recognition_particle_RNA wikiPageExternalLink Signal-Recognition-Particle.
- Signal_recognition_particle_RNA wikiPageExternalLink 947102.html.
- Signal_recognition_particle_RNA wikiPageID "12365585".
- Signal_recognition_particle_RNA wikiPageRevisionID "602998326".
- Signal_recognition_particle_RNA hasPhotoCollection Signal_recognition_particle_RNA.
- Signal_recognition_particle_RNA pdb ", , , , , , ,, , , , ,, ,".
- Signal_recognition_particle_RNA symbol "SRP RNA".
- Signal_recognition_particle_RNA subject Category:Non-coding_RNA.
- Signal_recognition_particle_RNA subject Category:Protein_biosynthesis.
- Signal_recognition_particle_RNA subject Category:RNA.
- Signal_recognition_particle_RNA type Biomolecule.
- Signal_recognition_particle_RNA type Protein.
- Signal_recognition_particle_RNA type BiologicalObject.
- Signal_recognition_particle_RNA comment "The signal recognition particle RNA, also known as 7SL, 6S, ffs, or 4.5S RNA, is the RNA component of the signal recognition particle (SRP) ribonucleoprotein complex. SRP is a universally conserved ribonucleoprotein that directs the traffic of proteins within the cell and allows them to be secreted. The SRP RNA, together with one or more SRP proteins contributes to the binding and release of the signal peptide.".
- Signal_recognition_particle_RNA label "7SL-RNA".
- Signal_recognition_particle_RNA label "Signal recognition particle RNA".
- Signal_recognition_particle_RNA sameAs 7SL-RNA.
- Signal_recognition_particle_RNA sameAs m.02w18cn.
- Signal_recognition_particle_RNA sameAs Q269987.
- Signal_recognition_particle_RNA sameAs Q269987.
- Signal_recognition_particle_RNA wasDerivedFrom Signal_recognition_particle_RNA?oldid=602998326.
- Signal_recognition_particle_RNA depiction HomosapiSRPRNA-2d.png.
- Signal_recognition_particle_RNA isPrimaryTopicOf Signal_recognition_particle_RNA.
