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- Small_Cajal_body_specific_RNA_17 abstract "Small Cajal body-specific RNA 17 (also known as U12-22 scaRNA) is a type of small nuclear RNA which localises to the cajal bodies and proposed to guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.The complete human U12-22/U4-8 scaRNA is composed of two tandem C/D box domains (termed U12-22 and U4-8). The 5' and 3' C/D domains are predicted to guide the 2'O-ribose methylation of residue U22 in U12 and residue C8 in U4 snRNAs respectively. This family includes only the 5' C/D box domain (U12-22) as the 3' C/D box is represented by Small Cajal body specific RNA 18. The 3' C/D domain (U4-8) was also cloned previously by Darzacq and called U91. Both the doublet (U12-22/U4-8) and singlet (U4-8) forms of this snRNA have been purified from HeLa cells. The doublet form U12-22/U4-8 has been shown to localise to the nucleoplasm and is proposed to reside in the Cajal bodies whereas the U4-8 single domain appears to accumulate in the nucleolus. In humans the genomic location of U12-88/U4-8 is intergenic and the purified transcript has been shown to possess a methylated guanosine cap suggesting it is independently transcribed by RNA polymerase II.".
- Small_Cajal_body_specific_RNA_17 thumbnail RF00492.jpg?width=300.
- Small_Cajal_body_specific_RNA_17 wikiPageID "11421542".
- Small_Cajal_body_specific_RNA_17 wikiPageRevisionID "505243077".
- Small_Cajal_body_specific_RNA_17 altsymbols "snoU12-22".
- Small_Cajal_body_specific_RNA_17 caption "Predicted secondary structure and sequence conservation of SCARNA17".
- Small_Cajal_body_specific_RNA_17 hasPhotoCollection Small_Cajal_body_specific_RNA_17.
- Small_Cajal_body_specific_RNA_17 id "RF00492".
- Small_Cajal_body_specific_RNA_17 name "small Cajal body-specific RNA 17".
- Small_Cajal_body_specific_RNA_17 rfam "RF00492".
- Small_Cajal_body_specific_RNA_17 rnaType Gene.
- Small_Cajal_body_specific_RNA_17 rnaType Small_Cajal_body-specific_RNA.
- Small_Cajal_body_specific_RNA_17 rnaType Small_nuclear_RNA.
- Small_Cajal_body_specific_RNA_17 rnaType Small_nucleolar_RNA.
- Small_Cajal_body_specific_RNA_17 symbol "SCARNA17".
- Small_Cajal_body_specific_RNA_17 taxDomain Eukaryote.
- Small_Cajal_body_specific_RNA_17 subject Category:Small_nuclear_RNA.
- Small_Cajal_body_specific_RNA_17 comment "Small Cajal body-specific RNA 17 (also known as U12-22 scaRNA) is a type of small nuclear RNA which localises to the cajal bodies and proposed to guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.The complete human U12-22/U4-8 scaRNA is composed of two tandem C/D box domains (termed U12-22 and U4-8). The 5' and 3' C/D domains are predicted to guide the 2'O-ribose methylation of residue U22 in U12 and residue C8 in U4 snRNAs respectively.".
- Small_Cajal_body_specific_RNA_17 label "Small Cajal body specific RNA 17".
- Small_Cajal_body_specific_RNA_17 sameAs m.02rb_r1.
- Small_Cajal_body_specific_RNA_17 sameAs Q7542717.
- Small_Cajal_body_specific_RNA_17 sameAs Q7542717.
- Small_Cajal_body_specific_RNA_17 wasDerivedFrom Small_Cajal_body_specific_RNA_17?oldid=505243077.
- Small_Cajal_body_specific_RNA_17 depiction RF00492.jpg.
- Small_Cajal_body_specific_RNA_17 isPrimaryTopicOf Small_Cajal_body_specific_RNA_17.