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- Spinorphin abstract "Spinorphin is an endogenous, non-classical opioid peptide of the hemorphin family first isolated from the bovine spinal cord (hence the prefix spin-) and acts as a regulator of the enkephalinases, a class of enzymes that break down endogenous the enkephalin peptides. It does so by inhibiting the enzymes aminopeptidase N (APN), dipeptidyl peptidase III (DPP3), angiotensin-converting enzyme (ACE), and neutral endopeptidase (NEP). Spinorphin is a heptapeptide and has the amino acid sequence Leu-Val-Val-Tyr-Pro-Trp-Thr (LVVYPWT). It has been observed to possess antinociceptive, antiallodynic, and anti-inflammatory properties. The mechanism of action of spinorphin has not been fully elucidated (i.e., how it acts to inhibit the enkephalinases), but it has been found to act as an antagonist of the P2X3 receptor, and as a weak partial agonist/antagonist of the FP1 receptor.".
- Spinorphin iupacName "(L)-leucyl-(L)-valyl-(L)-valyl-(L)-tyrosyl-(L)-prolyl-(L)-tryptophyl-(L)-threonine".
- Spinorphin thumbnail Spinorphin.svg?width=300.
- Spinorphin wikiPageID "33862311".
- Spinorphin wikiPageRevisionID "599128703".
- Spinorphin hasPhotoCollection Spinorphin.
- Spinorphin imagefile "Spinorphin.svg".
- Spinorphin imagesize "300".
- Spinorphin iupacname "(L)-leucyl-(L)-valyl-(L)-valyl-(L)-tyrosyl-(L)-prolyl-(L)-tryptophyl-(L)-threonine".
- Spinorphin othernames "LVVYPWT; LVV-hemorphin-4".
- Spinorphin subject Category:Opioid_peptides.
- Spinorphin type Abstraction100002137.
- Spinorphin type Amide114724264.
- Spinorphin type Chemical114806838.
- Spinorphin type Compound114818238.
- Spinorphin type Material114580897.
- Spinorphin type Matter100020827.
- Spinorphin type OrganicCompound114727670.
- Spinorphin type Part113809207.
- Spinorphin type Peptide114743046.
- Spinorphin type Peptides.
- Spinorphin type PhysicalEntity100001930.
- Spinorphin type Relation100031921.
- Spinorphin type Substance100019613.
- Spinorphin type ChemicalCompound.
- Spinorphin type ChemicalSubstance.
- Spinorphin type ChemicalObject.
- Spinorphin type Thing.
- Spinorphin comment "Spinorphin is an endogenous, non-classical opioid peptide of the hemorphin family first isolated from the bovine spinal cord (hence the prefix spin-) and acts as a regulator of the enkephalinases, a class of enzymes that break down endogenous the enkephalin peptides. It does so by inhibiting the enzymes aminopeptidase N (APN), dipeptidyl peptidase III (DPP3), angiotensin-converting enzyme (ACE), and neutral endopeptidase (NEP).".
- Spinorphin label "Spinorphin".
- Spinorphin sameAs m.0hnbxt7.
- Spinorphin sameAs Q7577645.
- Spinorphin sameAs Q7577645.
- Spinorphin sameAs Spinorphin.
- Spinorphin wasDerivedFrom Spinorphin?oldid=599128703.
- Spinorphin depiction Spinorphin.svg.
- Spinorphin isPrimaryTopicOf Spinorphin.