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- Spirapril abstract "Spirapril hydrochloride (Renormax) is an ACE inhibitor antihypertensive drug used to treat hypertension.It belongs to dicarboxy group of ace inhibitor.Like many ACE inhibitors, this is a prodrug which is converted to the active metabolite spiraprilat following oral administration. Unlike other members of the group, it is eliminated both by renal and hepatic routes which may allow for greater use in patients with renal impairment.However data on its effect upon the renal function is conflicting.It is produced synthetically by combining the following two pharmaceutical intermediates:(S)-1,4-Dithia-7-azaspiro(4,4)-nonane-8-carboxylic acid hydrobromide CAS 75776-79-3andN-[1-(S)-ethoxycarbonyl-3-phenylpropyl)-L-Alanine (ECPPA) [1]".
- Spirapril atcPrefix "C09".
- Spirapril atcSuffix "AA11".
- Spirapril bioavailability "50.0".
- Spirapril casNumber "83647-97-6".
- Spirapril drugbank "DB01348".
- Spirapril fdaUniiCode "96U2K78I3V".
- Spirapril iupacName "(8S)-7-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid".
- Spirapril pubchem "5311447".
- Spirapril thumbnail Spirapril.svg?width=300.
- Spirapril wikiPageID "4498883".
- Spirapril wikiPageRevisionID "606444526".
- Spirapril atcPrefix "9.0".
- Spirapril atcSuffix "AA11".
- Spirapril bioavailability "50.0".
- Spirapril c "22".
- Spirapril casNumber "83647".
- Spirapril chembl "431".
- Spirapril chemspiderid "4470933".
- Spirapril drugbank "DB01348".
- Spirapril eliminationHalfLife "126000.0".
- Spirapril excretion "Hepatic and renal".
- Spirapril h "30".
- Spirapril hasPhotoCollection Spirapril.
- Spirapril inchi "1".
- Spirapril inchikey "HRWCVUIFMSZDJS-SZMVWBNQBT".
- Spirapril iupacName "-7".
- Spirapril kegg "D08529".
- Spirapril legalStatus "Rx-only".
- Spirapril metabolism "converted to spiraprilat".
- Spirapril molecularWeight "466.616".
- Spirapril n "2".
- Spirapril o "5".
- Spirapril pregnancyCategory "D".
- Spirapril pubchem "5311447".
- Spirapril routesOfAdministration "Oral".
- Spirapril s "2".
- Spirapril smiles "O=C[C@@H]CCc3ccccc3".
- Spirapril stdinchi "1".
- Spirapril stdinchikey "HRWCVUIFMSZDJS-SZMVWBNQSA-N".
- Spirapril unii "96".
- Spirapril verifiedfields "changed".
- Spirapril verifiedrevid "409958627".
- Spirapril subject Category:ACE_inhibitors.
- Spirapril subject Category:Amides.
- Spirapril subject Category:Enantiopure_drugs.
- Spirapril subject Category:Ethyl_esters.
- Spirapril subject Category:Nitrogen_heterocycles.
- Spirapril subject Category:Prodrugs.
- Spirapril subject Category:Spiro_compounds.
- Spirapril subject Category:Sulfur_heterocycles.
- Spirapril type Abstraction100002137.
- Spirapril type Amide114724264.
- Spirapril type Amides.
- Spirapril type Chemical114806838.
- Spirapril type Cognition100023271.
- Spirapril type Compound105870180.
- Spirapril type Compound114818238.
- Spirapril type Concept105835747.
- Spirapril type Content105809192.
- Spirapril type Ester114850483.
- Spirapril type EthylEsters.
- Spirapril type HeterocyclicCompound115025397.
- Spirapril type Idea105833840.
- Spirapril type Material114580897.
- Spirapril type Matter100020827.
- Spirapril type NitrogenHeterocycles.
- Spirapril type OrganicCompound114727670.
- Spirapril type Part113809207.
- Spirapril type PhysicalEntity100001930.
- Spirapril type PsychologicalFeature100023100.
- Spirapril type Relation100031921.
- Spirapril type SpiroCompounds.
- Spirapril type Substance100019613.
- Spirapril type SulfurHeterocycles.
- Spirapril type Whole105869584.
- Spirapril type Drug.
- Spirapril type DrugProduct.
- Spirapril type FunctionalSubstance.
- Spirapril comment "Spirapril hydrochloride (Renormax) is an ACE inhibitor antihypertensive drug used to treat hypertension.It belongs to dicarboxy group of ace inhibitor.Like many ACE inhibitors, this is a prodrug which is converted to the active metabolite spiraprilat following oral administration.".
- Spirapril label "Spirapril".
- Spirapril label "Spirapril".
- Spirapril label "Spirapril".
- Spirapril label "Spirapryl".
- Spirapril sameAs Spirapril.
- Spirapril sameAs Spirapryl.
- Spirapril sameAs Spirapril.
- Spirapril sameAs m.0c5nqt.
- Spirapril sameAs Q835757.
- Spirapril sameAs Q835757.
- Spirapril sameAs DB01348.
- Spirapril sameAs Spirapril.
- Spirapril wasDerivedFrom Spirapril?oldid=606444526.
- Spirapril depiction Spirapril.svg.
- Spirapril isPrimaryTopicOf Spirapril.
