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• Strictosidine_synthase abstract "Strictosidine synthase (EC 4.3.3.2) a key enzyme in alkaloid biosynthesis. It catalyses the condensation of tryptamine with secologanin to form strictosidine:tryptamine + secologanin 3-alpha(S)-strictosidine + H2OThus, the two substrates of this enzyme are tryptamine and secologanin, whereas its two products are 3-alpha(S)-strictosidine and H2O. Since the condensation of tryptamine and secologanin is the first committed step in alkaloid synthesis, strictosidine synthase plays a fundamental role for the great majority of the indole-alkaloid pathways.This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. It can be isolated from several alkaloid-producing plants from the Apocynaceae family (e.g. Catharanthus roseus, Voacanga africana). The systematic name of this enzyme class is 3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming). Other names in common use include strictosidine synthetase, STR, and 3-alpha(S)-strictosidine tryptamine-lyase. Originally isolated from the plant Rauvolfia serpentina, a medicinal plant widely used in Indian folk medicine, this enzyme participates in terpenoid biosynthesis and indole and ipecac alkaloid biosynthesis, both of which produce many compounds with significant physiological and medicinal properties.".
• Strictosidine_synthase ecNumber "4.3.3.2".
• Strictosidine_synthase thumbnail Strictosidine_synthase_mechanism_(2-28-13,_v3).png?width=300.
• Strictosidine_synthase wikiPageID "14246825".
• Strictosidine_synthase wikiPageRevisionID "593101786".
• Strictosidine_synthase casNumber "69669".
• Strictosidine_synthase ecNumber "4.3".
• Strictosidine_synthase goCode "16844".
• Strictosidine_synthase hasPhotoCollection Strictosidine_synthase.
• Strictosidine_synthase iubmbEcNumber "4".
• Strictosidine_synthase name "strictosidine synthase".
• Strictosidine_synthase subject Category:EC_4.3.3.
• Strictosidine_synthase subject Category:Enzymes_of_known_structure.
• Strictosidine_synthase type Abstraction100002137.
• Strictosidine_synthase type Activator114723079.
• Strictosidine_synthase type Catalyst114723628.
• Strictosidine_synthase type Chemical114806838.
• Strictosidine_synthase type Compound114818238.
• Strictosidine_synthase type Enzyme114732946.
• Strictosidine_synthase type EnzymesOfKnownStructure.
• Strictosidine_synthase type Macromolecule114944888.
• Strictosidine_synthase type Material114580897.
• Strictosidine_synthase type Matter100020827.
• Strictosidine_synthase type Molecule114682133.
• Strictosidine_synthase type OrganicCompound114727670.
• Strictosidine_synthase type Part113809207.
• Strictosidine_synthase type PhysicalEntity100001930.
• Strictosidine_synthase type Protein114728724.
• Strictosidine_synthase type Relation100031921.
• Strictosidine_synthase type Substance100019613.
• Strictosidine_synthase type Thing100002452.
• Strictosidine_synthase type Unit109465459.
• Strictosidine_synthase type Biomolecule.
• Strictosidine_synthase type Enzyme.
• Strictosidine_synthase type BiologicalObject.
• Strictosidine_synthase comment "Strictosidine synthase (EC 4.3.3.2) a key enzyme in alkaloid biosynthesis. It catalyses the condensation of tryptamine with secologanin to form strictosidine:tryptamine + secologanin 3-alpha(S)-strictosidine + H2OThus, the two substrates of this enzyme are tryptamine and secologanin, whereas its two products are 3-alpha(S)-strictosidine and H2O.".
• Strictosidine_synthase label "Strictosidin-Synthase".
• Strictosidine_synthase label "Strictosidine synthase".
• Strictosidine_synthase sameAs Strictosidin-Synthase.
• Strictosidine_synthase sameAs m.03cz29c.
• Strictosidine_synthase sameAs Q2356161.
• Strictosidine_synthase sameAs Q2356161.
• Strictosidine_synthase sameAs Strictosidine_synthase.
• Strictosidine_synthase wasDerivedFrom Strictosidine_synthase?oldid=593101786.
• Strictosidine_synthase depiction Strictosidine_synthase_mechanism_(2-28-13,_v3).png.
• Strictosidine_synthase isPrimaryTopicOf Strictosidine_synthase.
• Strictosidine_synthase name "strictosidine synthase".