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- Surround_Optical_Fiber_Immunoassay abstract "Surround optical fiber immunoassay (SOFIA) is an ultrasensitive, in vitro diagnostic platform incorporating a surround optical fiber assembly that captures fluorescence emissions from an entire sample. The technology's defining characteristics are its extremely high limit of detection, sensitivity and dynamic range. SOFIA’s sensitivity is measured at the attogram level (10−18g), making it approximately one billion times more sensitive than conventional diagnostic techniques. Based on its enhanced dynamic range, SOFIA is able to discriminate levels of analyte in a sample over 10 orders of magnitude facilitating accurate titering.As a diagnostic platform, SOFIA has a broad range of applications. Several studies have already demonstrated SOFIA’s unprecedented ability to detect naturally occurring prions in the blood and urine of disease carriers. This is expected to lead to the first reliable ante mortem screening test for vCJD, BSE, scrapie, CWD, and other transmissible spongiform encephalopathies. Given the technology’s extreme sensitivity, additional unique applications are anticipated, including in vitro tests for other neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.SOFIA was developed as a result of a joint-collaborative research project between Los Alamos National Laboratory and State University of New York, and was supported by the Department of Defense's National Prion Research Program. Its ongoing development is being spearheaded by Bionosis, Inc., a private-sector biotechnology company.".
- Surround_Optical_Fiber_Immunoassay thumbnail SOFIA_platform.jpg?width=300.
- Surround_Optical_Fiber_Immunoassay wikiPageExternalLink video.htm.
- Surround_Optical_Fiber_Immunoassay wikiPageExternalLink index.htm.
- Surround_Optical_Fiber_Immunoassay wikiPageID "32823089".
- Surround_Optical_Fiber_Immunoassay wikiPageRevisionID "602442745".
- Surround_Optical_Fiber_Immunoassay acronym "SOFIA".
- Surround_Optical_Fiber_Immunoassay caption "A prototype version of surround optical fiber immunoassay .".
- Surround_Optical_Fiber_Immunoassay hasPhotoCollection Surround_Optical_Fiber_Immunoassay.
- Surround_Optical_Fiber_Immunoassay inventor "Los Alamos National Laboratory and SUNY".
- Surround_Optical_Fiber_Immunoassay model "Prototype".
- Surround_Optical_Fiber_Immunoassay name "Surround optical fiber immunoassay".
- Surround_Optical_Fiber_Immunoassay notableExperiments "Detection of prions in urine and blood of preclinical carriers".
- Surround_Optical_Fiber_Immunoassay uses "Medical, food safety, industrial, veterinary".
- Surround_Optical_Fiber_Immunoassay subject Category:Immunologic_tests.
- Surround_Optical_Fiber_Immunoassay subject Category:Laboratory_techniques.
- Surround_Optical_Fiber_Immunoassay subject Category:Medical_tests.
- Surround_Optical_Fiber_Immunoassay subject Category:Molecular_biology.
- Surround_Optical_Fiber_Immunoassay subject Category:Molecular_biology_techniques.
- Surround_Optical_Fiber_Immunoassay subject Category:Prions.
- Surround_Optical_Fiber_Immunoassay subject Category:Protein_methods.
- Surround_Optical_Fiber_Immunoassay comment "Surround optical fiber immunoassay (SOFIA) is an ultrasensitive, in vitro diagnostic platform incorporating a surround optical fiber assembly that captures fluorescence emissions from an entire sample. The technology's defining characteristics are its extremely high limit of detection, sensitivity and dynamic range. SOFIA’s sensitivity is measured at the attogram level (10−18g), making it approximately one billion times more sensitive than conventional diagnostic techniques.".
- Surround_Optical_Fiber_Immunoassay label "Surround Optical Fiber Immunoassay".
- Surround_Optical_Fiber_Immunoassay sameAs m.0h3lqgk.
- Surround_Optical_Fiber_Immunoassay sameAs Q7646898.
- Surround_Optical_Fiber_Immunoassay sameAs Q7646898.
- Surround_Optical_Fiber_Immunoassay wasDerivedFrom Surround_Optical_Fiber_Immunoassay?oldid=602442745.
- Surround_Optical_Fiber_Immunoassay depiction SOFIA_platform.jpg.
- Surround_Optical_Fiber_Immunoassay isPrimaryTopicOf Surround_Optical_Fiber_Immunoassay.
