Matches in DBpedia 2014 for { <http://dbpedia.org/resource/T-type_calcium_channel> ?p ?o. }
Showing items 1 to 99 of
99
with 100 items per page.
- T-type_calcium_channel abstract "T-type calcium channels are low-voltage activated calcium channels that open during membrane depolarization. These channels aid in mediating calcium influx into cells after an action potential or depolarizing signal. The entry of calcium into various cells has many different physiological responses associated with it. Within cardiac and smooth muscle cells voltage-gated calcium channel activation initiates contraction directly by allowing the cytosolic calcium concentration to increase. Not only are T-type calcium channels known to be present within cardiac and smooth muscle, but also are present in many neuronal cells within the central nervous system. Different experimental studies within the 1970s allowed for the distinction of T-type calcium channels (transient opening calcium channels) from the already well-known L-type calcium channels (low-voltage opening calcium channels). The new T-type channels were much different from the L-type calcium channels due to their ability to be activated by more negative membrane potentials, had small single channel conductance, and also were unresponsive to calcium antagonist drugs that were present. These distinct calcium channels are generally located within the brain, peripheral nervous system, heart, smooth muscle, bone, and endocrine system.The distinct structures of T-type calcium channels are what allow them to conduct in these manners, consisting of a primary α1 subunit. The α1 subunit of T-type channels is the primary subunit that forms the pore of the channel, and allows for entry of calcium.T-type calcium channels function to control the pace-making activity of the SA Node within the heart and relay rapid action potentials within the thalamus. These channels allow for continuous rhythmic bursts that control the SA Node of the heart.Pharmacological evidence of T-type calcium channels suggest that they play a key role in diseases such as absence epilepsy, diabetes, and several forms of cancer. Further research is continuously occurring to better understand these distinct channels, as well as create drugs to select for these channels.".
- T-type_calcium_channel arm "p".
- T-type_calcium_channel arm "q".
- T-type_calcium_channel band "13.1".
- T-type_calcium_channel band "13.3".
- T-type_calcium_channel band "22".
- T-type_calcium_channel chromosome "16".
- T-type_calcium_channel chromosome "17".
- T-type_calcium_channel chromosome "22".
- T-type_calcium_channel entrezgene "8911".
- T-type_calcium_channel entrezgene "8912".
- T-type_calcium_channel hgncid "1394".
- T-type_calcium_channel hgncid "1395".
- T-type_calcium_channel hgncid "1396".
- T-type_calcium_channel omim "604065".
- T-type_calcium_channel omim "607904".
- T-type_calcium_channel omim "608230".
- T-type_calcium_channel refseq "NM_001003406".
- T-type_calcium_channel refseq "NM_001005407".
- T-type_calcium_channel refseq "NM_018896".
- T-type_calcium_channel symbol "CACNA1G".
- T-type_calcium_channel symbol "CACNA1H".
- T-type_calcium_channel symbol "CACNA1I".
- T-type_calcium_channel uniprot "O43497".
- T-type_calcium_channel uniprot "O95180".
- T-type_calcium_channel uniprot "Q9P0X4".
- T-type_calcium_channel wikiPageID "9773346".
- T-type_calcium_channel wikiPageRevisionID "605494337".
- T-type_calcium_channel arm "p".
- T-type_calcium_channel arm "q".
- T-type_calcium_channel band "13.1".
- T-type_calcium_channel band "13.3".
- T-type_calcium_channel band "22".
- T-type_calcium_channel chromosome "16".
- T-type_calcium_channel chromosome "17".
- T-type_calcium_channel chromosome "22".
- T-type_calcium_channel entrezgene "8911".
- T-type_calcium_channel entrezgene "8912".
- T-type_calcium_channel hasPhotoCollection T-type_calcium_channel.
- T-type_calcium_channel hgncid "1394".
- T-type_calcium_channel hgncid "1395".
- T-type_calcium_channel hgncid "1396".
- T-type_calcium_channel iupharId "yes".
- T-type_calcium_channel name CACNA1G.
- T-type_calcium_channel name CACNA1H.
- T-type_calcium_channel name CACNA1I.
- T-type_calcium_channel omim "604065".
- T-type_calcium_channel omim "607904".
- T-type_calcium_channel omim "608230".
- T-type_calcium_channel refseq "NM_001003406".
- T-type_calcium_channel refseq "NM_001005407".
- T-type_calcium_channel refseq "NM_018896".
- T-type_calcium_channel symbol "CACNA1G".
- T-type_calcium_channel symbol "CACNA1H".
- T-type_calcium_channel symbol "CACNA1I".
- T-type_calcium_channel uniprot "O43497".
- T-type_calcium_channel uniprot "O95180".
- T-type_calcium_channel uniprot "Q9P0X4".
- T-type_calcium_channel type Abstraction100002137.
- T-type_calcium_channel type Act100030358.
- T-type_calcium_channel type Channel106259898.
- T-type_calcium_channel type Chemical114806838.
- T-type_calcium_channel type Communication106252138.
- T-type_calcium_channel type Compound114818238.
- T-type_calcium_channel type Event100029378.
- T-type_calcium_channel type IntegralMembraneProteins.
- T-type_calcium_channel type IonChannels.
- T-type_calcium_channel type Macromolecule114944888.
- T-type_calcium_channel type Material114580897.
- T-type_calcium_channel type Matter100020827.
- T-type_calcium_channel type Molecule114682133.
- T-type_calcium_channel type OrganicCompound114727670.
- T-type_calcium_channel type Part113809207.
- T-type_calcium_channel type PhysicalEntity100001930.
- T-type_calcium_channel type Protein114728724.
- T-type_calcium_channel type PsychologicalFeature100023100.
- T-type_calcium_channel type Relation100031921.
- T-type_calcium_channel type Substance100019613.
- T-type_calcium_channel type Thing100002452.
- T-type_calcium_channel type Transmission106251781.
- T-type_calcium_channel type Unit109465459.
- T-type_calcium_channel type YagoPermanentlyLocatedEntity.
- T-type_calcium_channel type Biomolecule.
- T-type_calcium_channel type Protein.
- T-type_calcium_channel type ProteinMolecule.
- T-type_calcium_channel type BiologicalObject.
- T-type_calcium_channel comment "T-type calcium channels are low-voltage activated calcium channels that open during membrane depolarization. These channels aid in mediating calcium influx into cells after an action potential or depolarizing signal. The entry of calcium into various cells has many different physiological responses associated with it. Within cardiac and smooth muscle cells voltage-gated calcium channel activation initiates contraction directly by allowing the cytosolic calcium concentration to increase.".
- T-type_calcium_channel label "T-type calcium channel".
- T-type_calcium_channel label "T-type calciumkanaal".
- T-type_calcium_channel sameAs T-type_calciumkanaal.
- T-type_calcium_channel sameAs m.02prs7p.
- T-type_calcium_channel sameAs Q2487620.
- T-type_calcium_channel sameAs Q2487620.
- T-type_calcium_channel sameAs T-type_calcium_channel.
- T-type_calcium_channel wasDerivedFrom T-type_calcium_channel?oldid=605494337.
- T-type_calcium_channel isPrimaryTopicOf T-type_calcium_channel.
- T-type_calcium_channel name "Calcium channel, voltage-dependent, T-type, alpha 1G subunit".
- T-type_calcium_channel name "Calcium channel, voltage-dependent, T-type, alpha 1H subunit".
- T-type_calcium_channel name "Calcium channel, voltage-dependent, T-type, alpha 1I subunit".