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- TAF10 abstract "Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.".
- TAF10 entrezgene "6881".
- TAF10 wikiPageID "14762392".
- TAF10 wikiPageRevisionID "593121549".
- TAF10 hasPhotoCollection TAF10.
- TAF10 requireManualInspection "no".
- TAF10 summaryText "Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.".
- TAF10 updateCitations "yes".
- TAF10 updatePage "yes".
- TAF10 updateProteinBox "yes".
- TAF10 updateSummary "yes".
- TAF10 type Biomolecule.
- TAF10 type Protein.
- TAF10 type BiologicalObject.
- TAF10 comment "Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.".
- TAF10 label "TAF10".
- TAF10 label "TAF10".
- TAF10 sameAs TAF10.
- TAF10 sameAs m.03gx3fw.
- TAF10 sameAs Q9081193.
- TAF10 sameAs Q9081193.
- TAF10 wasDerivedFrom TAF10?oldid=593121549.
- TAF10 isPrimaryTopicOf TAF10.