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- TAF11 abstract "Transcription initiation factor TFIID subunit 11 also known as TAFII28, is a protein that in humans is encoded by the TAF11 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.".
- TAF11 entrezgene "6882".
- TAF11 symbol "TAFII28".
- TAF11 thumbnail PDB_1bh9_EBI.jpg?width=300.
- TAF11 wikiPageID "14774820".
- TAF11 wikiPageRevisionID "593121565".
- TAF11 caption "htafii18/htafii28 heterodimer crystal structure with bound pcmbs".
- TAF11 hasPhotoCollection TAF11.
- TAF11 interpro "IPR006809".
- TAF11 name "TAFII28".
- TAF11 pfam "PF04719".
- TAF11 pfamClan "CL0012".
- TAF11 requireManualInspection "no".
- TAF11 scop "1".
- TAF11 summaryText "Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.".
- TAF11 symbol "TAFII28".
- TAF11 updateCitations "yes".
- TAF11 updatePage "yes".
- TAF11 updateProteinBox "yes".
- TAF11 updateSummary "yes".
- TAF11 type Biomolecule.
- TAF11 type Protein.
- TAF11 type BiologicalObject.
- TAF11 comment "Transcription initiation factor TFIID subunit 11 also known as TAFII28, is a protein that in humans is encoded by the TAF11 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides.".
- TAF11 label "TAF11".
- TAF11 label "TAF11".
- TAF11 sameAs TAF11.
- TAF11 sameAs m.03gxlgz.
- TAF11 sameAs Q7669227.
- TAF11 sameAs Q7669227.
- TAF11 wasDerivedFrom TAF11?oldid=593121565.
- TAF11 depiction PDB_1bh9_EBI.jpg.
- TAF11 isPrimaryTopicOf TAF11.
