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- TAF15 abstract "TATA-binding protein-associated factor 2N is a protein that in humans is encoded by the TAF15 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.".
- TAF15 entrezgene "8148".
- TAF15 wikiPageID "14774906".
- TAF15 wikiPageRevisionID "593121590".
- TAF15 hasPhotoCollection TAF15.
- TAF15 requireManualInspection "no".
- TAF15 summaryText "Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified.".
- TAF15 updateCitations "yes".
- TAF15 updatePage "yes".
- TAF15 updateProteinBox "yes".
- TAF15 updateSummary "yes".
- TAF15 type Biomolecule.
- TAF15 type Protein.
- TAF15 type BiologicalObject.
- TAF15 comment "TATA-binding protein-associated factor 2N is a protein that in humans is encoded by the TAF15 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.".
- TAF15 label "TAF15".
- TAF15 sameAs m.03gxln4.
- TAF15 sameAs Q7669226.
- TAF15 sameAs Q7669226.
- TAF15 wasDerivedFrom TAF15?oldid=593121590.
- TAF15 isPrimaryTopicOf TAF15.