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- TAF5 abstract "Transcription initiation factor TFIID subunit 5 is a protein that in humans is encoded by the TAF5 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex.".
- TAF5 entrezgene "6877".
- TAF5 wikiPageID "14763553".
- TAF5 wikiPageRevisionID "593121666".
- TAF5 hasPhotoCollection TAF5.
- TAF5 requireManualInspection "no".
- TAF5 summaryText "Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex.".
- TAF5 updateCitations "yes".
- TAF5 updatePage "yes".
- TAF5 updateProteinBox "yes".
- TAF5 updateSummary "yes".
- TAF5 type Biomolecule.
- TAF5 type Protein.
- TAF5 type BiologicalObject.
- TAF5 comment "Transcription initiation factor TFIID subunit 5 is a protein that in humans is encoded by the TAF5 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.".
- TAF5 label "TAF5".
- TAF5 sameAs m.03gx5jx.
- TAF5 sameAs Q7669238.
- TAF5 sameAs Q7669238.
- TAF5 wasDerivedFrom TAF5?oldid=593121666.
- TAF5 isPrimaryTopicOf TAF5.