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- TBPL1 abstract "TATA box-binding protein-like protein 1 is a protein that in humans is encoded by the TBPL1 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.".
- TBPL1 entrezgene "9519".
- TBPL1 wikiPageID "15181699".
- TBPL1 wikiPageRevisionID "602199446".
- TBPL1 hasPhotoCollection TBPL1.
- TBPL1 requireManualInspection "no".
- TBPL1 summaryText "Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID , which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.".
- TBPL1 updateCitations "yes".
- TBPL1 updatePage "yes".
- TBPL1 updateProteinBox "yes".
- TBPL1 updateSummary "yes".
- TBPL1 subject Category:Transcription_factors.
- TBPL1 type Biomolecule.
- TBPL1 type Protein.
- TBPL1 type BiologicalObject.
- TBPL1 comment "TATA box-binding protein-like protein 1 is a protein that in humans is encoded by the TBPL1 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals.".
- TBPL1 label "TBPL1".
- TBPL1 sameAs m.03hl292.
- TBPL1 sameAs Q7669560.
- TBPL1 sameAs Q7669560.
- TBPL1 wasDerivedFrom TBPL1?oldid=602199446.
- TBPL1 isPrimaryTopicOf TBPL1.