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- TCEB2 abstract "Transcription elongation factor B polypeptide 2 is a protein that in humans is encoded by the TCEB2 gene.This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.".
- TCEB2 entrezgene "6923".
- TCEB2 wikiPageID "14166184".
- TCEB2 wikiPageRevisionID "602199484".
- TCEB2 hasPhotoCollection TCEB2.
- TCEB2 requireManualInspection "no".
- TCEB2 summaryText "This gene encodes the protein elongin B, which is a subunit of the transcription factor B complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.".
- TCEB2 updateCitations "yes".
- TCEB2 updatePage "yes".
- TCEB2 updateProteinBox "yes".
- TCEB2 updateSummary "yes".
- TCEB2 type Biomolecule.
- TCEB2 type Protein.
- TCEB2 type BiologicalObject.
- TCEB2 comment "Transcription elongation factor B polypeptide 2 is a protein that in humans is encoded by the TCEB2 gene.This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.".
- TCEB2 label "TCEB2".
- TCEB2 sameAs m.03cwmly.
- TCEB2 sameAs Q15997188.
- TCEB2 sameAs Q15997188.
- TCEB2 wasDerivedFrom TCEB2?oldid=602199484.
- TCEB2 isPrimaryTopicOf TCEB2.