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- TCEB3 abstract "Transcription elongation factor B polypeptide 3 is a protein that in humans is encoded by the TCEB3 gene.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.".
- TCEB3 entrezgene "6924".
- TCEB3 wikiPageID "14795939".
- TCEB3 wikiPageRevisionID "601784260".
- TCEB3 hasPhotoCollection TCEB3.
- TCEB3 requireManualInspection "no".
- TCEB3 summaryText "This gene encodes the protein elongin A, which is a subunit of the transcription factor B complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.".
- TCEB3 updateCitations "yes".
- TCEB3 updatePage "yes".
- TCEB3 updateProteinBox "yes".
- TCEB3 updateSummary "yes".
- TCEB3 type Biomolecule.
- TCEB3 type Protein.
- TCEB3 type BiologicalObject.
- TCEB3 comment "Transcription elongation factor B polypeptide 3 is a protein that in humans is encoded by the TCEB3 gene.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units.".
- TCEB3 label "TCEB3".
- TCEB3 sameAs m.03gy6lk.
- TCEB3 sameAs Q7669669.
- TCEB3 sameAs Q7669669.
- TCEB3 wasDerivedFrom TCEB3?oldid=601784260.
- TCEB3 isPrimaryTopicOf TCEB3.