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- TLR_1 abstract "TLR 1 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. TLR1 recognizes pathogen-associated molecular pattern with a specificity for gram-positive bacteria. TLR1 has also been designated as CD281 (cluster of differentiation 281).TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.TLR1 recognises peptidoglycan and (triacyl) lipoproteins in concert with TLR2 (as a heterodimer). It is found on the surface of macrophages and neutrophils.".
- TLR_1 entrezgene "7096".
- TLR_1 wikiPageExternalLink entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7096.
- TLR_1 wikiPageID "10829624".
- TLR_1 wikiPageRevisionID "602210052".
- TLR_1 hasPhotoCollection TLR_1.
- TLR_1 requireManualInspection "no".
- TLR_1 updateCitations "no".
- TLR_1 updatePage "yes".
- TLR_1 updateProteinBox "yes".
- TLR_1 updateSummary "no".
- TLR_1 subject Category:Clusters_of_differentiation.
- TLR_1 subject Category:Toll-like_receptors.
- TLR_1 type Biomolecule.
- TLR_1 type Protein.
- TLR_1 type BiologicalObject.
- TLR_1 comment "TLR 1 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. TLR1 recognizes pathogen-associated molecular pattern with a specificity for gram-positive bacteria. TLR1 has also been designated as CD281 (cluster of differentiation 281).TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.".
- TLR_1 label "TLR 1".
- TLR_1 label "TLR1".
- TLR_1 label "Толл-подобный рецептор 1".
- TLR_1 sameAs TLR1.
- TLR_1 sameAs TLR1.
- TLR_1 sameAs m.02qrbn5.
- TLR_1 sameAs Q4459741.
- TLR_1 sameAs Q4459741.
- TLR_1 sameAs 173.
- TLR_1 sameAs 2090.
- TLR_1 sameAs 2112.
- TLR_1 wasDerivedFrom TLR_1?oldid=602210052.
- TLR_1 isPrimaryTopicOf TLR_1.