Matches in DBpedia 2014 for { <http://dbpedia.org/resource/TOB1> ?p ?o. }
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- TOB1 abstract "Protein Tob1 is a protein that in humans is encoded by the TOB1 gene.This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phosphorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.".
- TOB1 entrezgene "10140".
- TOB1 wikiPageID "14773096".
- TOB1 wikiPageRevisionID "593198650".
- TOB1 hasPhotoCollection TOB1.
- TOB1 requireManualInspection "no".
- TOB1 summaryText "This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phosphorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.".
- TOB1 updateCitations "yes".
- TOB1 updatePage "yes".
- TOB1 updateProteinBox "yes".
- TOB1 updateSummary "yes".
- TOB1 type Biomolecule.
- TOB1 type Protein.
- TOB1 type BiologicalObject.
- TOB1 comment "Protein Tob1 is a protein that in humans is encoded by the TOB1 gene.This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phosphorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase.".
- TOB1 label "TOB1".
- TOB1 label "TOB1".
- TOB1 sameAs TOB1.
- TOB1 sameAs m.03gxj60.
- TOB1 sameAs Q7670952.
- TOB1 sameAs Q7670952.
- TOB1 wasDerivedFrom TOB1?oldid=593198650.
- TOB1 isPrimaryTopicOf TOB1.