Matches in DBpedia 2014 for { <http://dbpedia.org/resource/TOP3B> ?p ?o. }
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- TOP3B abstract "DNA topoisomerase 3-beta-1 is an enzyme that in humans is encoded by the TOP3B gene.This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.".
- TOP3B entrezgene "8940".
- TOP3B wikiPageID "14876068".
- TOP3B wikiPageRevisionID "601785545".
- TOP3B hasPhotoCollection TOP3B.
- TOP3B requireManualInspection "no".
- TOP3B summaryText "This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.".
- TOP3B updateCitations "yes".
- TOP3B updatePage "yes".
- TOP3B updateProteinBox "yes".
- TOP3B updateSummary "yes".
- TOP3B type Biomolecule.
- TOP3B type Protein.
- TOP3B type BiologicalObject.
- TOP3B comment "DNA topoisomerase 3-beta-1 is an enzyme that in humans is encoded by the TOP3B gene.This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA.".
- TOP3B label "TOP3B".
- TOP3B sameAs m.03g_wxp.
- TOP3B sameAs Q7671017.
- TOP3B sameAs Q7671017.
- TOP3B wasDerivedFrom TOP3B?oldid=601785545.
- TOP3B isPrimaryTopicOf TOP3B.