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- TP-003 abstract "TP-003 is an anxiolytic drug with a novel chemical structure, which is used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It is a subtype-selective partial agonist at GABAA receptors, binding to GABAA receptor complexes bearing either α2, α3 or α5 subunits, but only showing significant efficacy at α3. It has modest anticonvulsant activity although less than that of diazepam, and its main effect is likely to be selective anxiolytic action, as seen with other related α3-preferring agonists such as L-838,417.".
- TP-003 casNumber "628690-75-5".
- TP-003 iupacName "4,2'-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]biphenyl-2-carbonitrile".
- TP-003 pubchem "9978724".
- TP-003 thumbnail TP-003.png?width=300.
- TP-003 wikiPageID "18795045".
- TP-003 wikiPageRevisionID "529918801".
- TP-003 c "23".
- TP-003 casNumber "628690".
- TP-003 f "3".
- TP-003 h "16".
- TP-003 hasPhotoCollection TP-003.
- TP-003 iupacName "42".
- TP-003 molecularWeight "407.387".
- TP-003 n "3".
- TP-003 o "1".
- TP-003 pubchem "9978724".
- TP-003 smiles "N#Cc4ccccc4-c1cc-c2cnc3n2cccc3F".
- TP-003 verifiedrevid "376274694".
- TP-003 subject Category:Alcohols.
- TP-003 subject Category:Anxiolytics.
- TP-003 subject Category:Imidazopyridines.
- TP-003 subject Category:Nitriles.
- TP-003 subject Category:Organofluorides.
- TP-003 type Drug.
- TP-003 type DrugProduct.
- TP-003 type FunctionalSubstance.
- TP-003 comment "TP-003 is an anxiolytic drug with a novel chemical structure, which is used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. It is a subtype-selective partial agonist at GABAA receptors, binding to GABAA receptor complexes bearing either α2, α3 or α5 subunits, but only showing significant efficacy at α3.".
- TP-003 label "TP-003".
- TP-003 sameAs m.04gj7gf.
- TP-003 sameAs Q7671083.
- TP-003 sameAs Q7671083.
- TP-003 wasDerivedFrom TP-003?oldid=529918801.
- TP-003 depiction TP-003.png.
- TP-003 isPrimaryTopicOf TP-003.
