Matches in DBpedia 2014 for { <http://dbpedia.org/resource/TPBG> ?p ?o. }
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- TPBG abstract "Trophoblast glycoprotein, also known as TPBG or 5T4, is a human gene.5T4 is an antigen expressed in a number of carcinomas. It is an N-glycosylated transmembrane 72 kDa glycoprotein containing seven leucine-rich repeat regions. 5T4 is often referred to as an oncofetal antigen due to its expression in foetal trophoblast (where it was first discovered) or trophoblast glycoprotein (TPBG).5T4 is found in tumors including the colorectal, ovarian, and gastric. Its expression is used as a prognostic aid in these cases. It has very limited expression in normal tissue but is widespread in malignant tumors throughout their development.Its confined expression appears to give 5T4 the potential to be useful in cancer immunotherapy. There has been extensive research into its role in antibody-directed immunotherapy through the use of the high-affinity murine monoclonal antibody, mAb5T4, to deliver response modifiers (such as staphylococcus aureus superantigen) accurately to a tumor.5T4 is also the target of the cancer vaccine TroVax which is in clinical trials for the treatment of a range of different solid tumour types.".
- TPBG entrezgene "7162".
- TPBG wikiPageID "14881584".
- TPBG wikiPageRevisionID "593208449".
- TPBG hasPhotoCollection TPBG.
- TPBG requireManualInspection "no".
- TPBG updateCitations "yes".
- TPBG updatePage "yes".
- TPBG updateProteinBox "yes".
- TPBG updateSummary "no".
- TPBG subject Category:Immunology.
- TPBG type Biomolecule.
- TPBG type Protein.
- TPBG type BiologicalObject.
- TPBG comment "Trophoblast glycoprotein, also known as TPBG or 5T4, is a human gene.5T4 is an antigen expressed in a number of carcinomas. It is an N-glycosylated transmembrane 72 kDa glycoprotein containing seven leucine-rich repeat regions. 5T4 is often referred to as an oncofetal antigen due to its expression in foetal trophoblast (where it was first discovered) or trophoblast glycoprotein (TPBG).5T4 is found in tumors including the colorectal, ovarian, and gastric.".
- TPBG label "TPBG".
- TPBG sameAs m.03h08j_.
- TPBG sameAs Q7671103.
- TPBG sameAs Q7671103.
- TPBG wasDerivedFrom TPBG?oldid=593208449.
- TPBG isPrimaryTopicOf TPBG.