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- TPP_riboswitch abstract "The TPP riboswitch, also known as the THI element and Thi-box riboswitch, is a highly conserved RNA secondary structure. It serves as a riboswitch that binds directly to thiamine pyrophosphate (TPP) to regulate gene expression through a variety of mechanisms in archaea, bacteria and eukaryotes. TPP is the active form of thiamine (vitamin B1), an essential coenzyme synthesised by coupling of pyrimidine and thiazole moieties in bacteria. The THI element is an extension of a previously detected thiamin-regulatory element, the thi box, there is considerable variability in the predicted length and structures of the additional and facultative stem loops represented in dark blue in the secondary structure diagram Analysis of operon structures has identified a large number of new candidate thiamin-regulated genes, mostly transporters, in various prokaryotic organisms. The x-ray crystal structure of the TPP riboswitch aptamer has been solved.".
- TPP_riboswitch thumbnail RF00059.jpg?width=300.
- TPP_riboswitch wikiPageExternalLink explore.cgi?pdbId=2HOJ.
- TPP_riboswitch wikiPageID "11422340".
- TPP_riboswitch wikiPageRevisionID "548718909".
- TPP_riboswitch altsymbols "THI".
- TPP_riboswitch caption "Predicted secondary structure and sequence conservation of TPP".
- TPP_riboswitch hasPhotoCollection TPP_riboswitch.
- TPP_riboswitch id "RF00059".
- TPP_riboswitch name "TPP riboswitch".
- TPP_riboswitch rfam "RF00059".
- TPP_riboswitch rnaType Cis-regulatory_element.
- TPP_riboswitch rnaType Riboswitch.
- TPP_riboswitch symbol "TPP".
- TPP_riboswitch taxDomain Archaea.
- TPP_riboswitch taxDomain Bacteria.
- TPP_riboswitch taxDomain Eukaryote.
- TPP_riboswitch subject Category:Cis-regulatory_RNA_elements.
- TPP_riboswitch subject Category:Riboswitch.
- TPP_riboswitch type Abstraction100002137.
- TPP_riboswitch type Cis-regulatoryRNAElements.
- TPP_riboswitch type Cognition100023271.
- TPP_riboswitch type Component105868954.
- TPP_riboswitch type Concept105835747.
- TPP_riboswitch type Content105809192.
- TPP_riboswitch type Idea105833840.
- TPP_riboswitch type Part105867413.
- TPP_riboswitch type PsychologicalFeature100023100.
- TPP_riboswitch comment "The TPP riboswitch, also known as the THI element and Thi-box riboswitch, is a highly conserved RNA secondary structure. It serves as a riboswitch that binds directly to thiamine pyrophosphate (TPP) to regulate gene expression through a variety of mechanisms in archaea, bacteria and eukaryotes. TPP is the active form of thiamine (vitamin B1), an essential coenzyme synthesised by coupling of pyrimidine and thiazole moieties in bacteria.".
- TPP_riboswitch label "TPP riboswitch".
- TPP_riboswitch sameAs m.02rc3dm.
- TPP_riboswitch sameAs Q7671181.
- TPP_riboswitch sameAs Q7671181.
- TPP_riboswitch sameAs TPP_riboswitch.
- TPP_riboswitch wasDerivedFrom TPP_riboswitch?oldid=548718909.
- TPP_riboswitch depiction RF00059.jpg.
- TPP_riboswitch isPrimaryTopicOf TPP_riboswitch.