Matches in DBpedia 2014 for { <http://dbpedia.org/resource/TRAF1> ?p ?o. }
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- TRAF1 abstract "TNF receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.".
- TRAF1 entrezgene "7185".
- TRAF1 wikiPageID "14131769".
- TRAF1 wikiPageRevisionID "593209444".
- TRAF1 hasPhotoCollection TRAF1.
- TRAF1 requireManualInspection "no".
- TRAF1 summaryText "The protein encoded by this gene is a member of the TNF receptor associated factor protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins , and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus . EBV infection membrane protein 1 is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.".
- TRAF1 updateCitations "yes".
- TRAF1 updatePage "yes".
- TRAF1 updateProteinBox "yes".
- TRAF1 updateSummary "yes".
- TRAF1 type Biomolecule.
- TRAF1 type Protein.
- TRAF1 type BiologicalObject.
- TRAF1 comment "TNF receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB.".
- TRAF1 label "TRAF1".
- TRAF1 sameAs m.03cvkmc.
- TRAF1 sameAs Q7671244.
- TRAF1 sameAs Q7671244.
- TRAF1 wasDerivedFrom TRAF1?oldid=593209444.
- TRAF1 isPrimaryTopicOf TRAF1.