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- TRNA-dihydrouridine_synthase abstract "In molecular biology, tRNA-dihydrouridine synthase is a family of enzymes which catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archaea. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA. It is likely that different family members have different substrate specificities, which may overlap. Dus 1 from Saccharomyces cerevisiae (Baker's yeast) acts on pre-tRNA-Phe, while Dus 2 acts on pre-tRNA-Tyr and pre-tRNA-Leu. Dus 1 is active as a single subunit, requiring NADPH or NADH, and is stimulated by the presence of FAD. Some family members may be targeted to the mitochondria and even have a role in mitochondria.".
- TRNA-dihydrouridine_synthase symbol "Dus".
- TRNA-dihydrouridine_synthase thumbnail PDB_1vhn_EBI.jpg?width=300.
- TRNA-dihydrouridine_synthase wikiPageID "32634027".
- TRNA-dihydrouridine_synthase wikiPageRevisionID "593218051".
- TRNA-dihydrouridine_synthase caption "crystal structure of a putative flavin oxidoreductase with flavin".
- TRNA-dihydrouridine_synthase hasPhotoCollection TRNA-dihydrouridine_synthase.
- TRNA-dihydrouridine_synthase interpro "IPR001269".
- TRNA-dihydrouridine_synthase name "Dihydrouridine synthase".
- TRNA-dihydrouridine_synthase pfam "PF01207".
- TRNA-dihydrouridine_synthase pfamClan "CL0036".
- TRNA-dihydrouridine_synthase prosite "PDOC00874".
- TRNA-dihydrouridine_synthase scop "1".
- TRNA-dihydrouridine_synthase symbol "Dus".
- TRNA-dihydrouridine_synthase subject Category:Protein_families.
- TRNA-dihydrouridine_synthase type Abstraction100002137.
- TRNA-dihydrouridine_synthase type Family108078020.
- TRNA-dihydrouridine_synthase type Group100031264.
- TRNA-dihydrouridine_synthase type Organization108008335.
- TRNA-dihydrouridine_synthase type ProteinFamilies.
- TRNA-dihydrouridine_synthase type SocialGroup107950920.
- TRNA-dihydrouridine_synthase type Unit108189659.
- TRNA-dihydrouridine_synthase type YagoLegalActor.
- TRNA-dihydrouridine_synthase type YagoLegalActorGeo.
- TRNA-dihydrouridine_synthase type YagoPermanentlyLocatedEntity.
- TRNA-dihydrouridine_synthase type Biomolecule.
- TRNA-dihydrouridine_synthase type Protein.
- TRNA-dihydrouridine_synthase type BiologicalObject.
- TRNA-dihydrouridine_synthase comment "In molecular biology, tRNA-dihydrouridine synthase is a family of enzymes which catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archaea. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown, but may increase conformational flexibility of the tRNA.".
- TRNA-dihydrouridine_synthase label "TRNA-dihydrouridine synthase".
- TRNA-dihydrouridine_synthase sameAs m.0h3rpn0.
- TRNA-dihydrouridine_synthase sameAs Q7671420.
- TRNA-dihydrouridine_synthase sameAs Q7671420.
- TRNA-dihydrouridine_synthase sameAs TRNA-dihydrouridine_synthase.
- TRNA-dihydrouridine_synthase wasDerivedFrom TRNA-dihydrouridine_synthase?oldid=593218051.
- TRNA-dihydrouridine_synthase depiction PDB_1vhn_EBI.jpg.
- TRNA-dihydrouridine_synthase isPrimaryTopicOf TRNA-dihydrouridine_synthase.