Matches in DBpedia 2014 for { <http://dbpedia.org/resource/TRPML> ?p ?o. }
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- TRPML abstract "TRPML (transient receptor potential cation channel, mucolipin subfamily) comprises a group of three evolutionarily related proteins that belongs to the large family of transient receptor potential ion channels. The three proteins TRPML1, TRPML2 and TRPML3 are encoded by the mucolipin-1 (MCOLN1), mucolipin-2 (MCOLN2) and mucolipin-3 (MCOLN3) genes, respectively. The three members of the TRPML ("ML" for mucolipin) sub-family are not extremely well characterized. TRPML1 is known to be localized in late endosomes. This subunit also contains a lipase domain between its S1 and S2 segments. While the function of this domain is unknown it has been proposed that it is involved in channel regulation. Physiological studies have described TRPML1 channels as proton leak channels in lysosomes responsible for preventing these organelles from becoming too acidic. TRPML2 and TRPML3 more poorly characterized than TRPML1.Deficiencies can lead to enlarged vesicles.".
- TRPML wikiPageExternalLink FamilyMenuForward?familyId=12.
- TRPML wikiPageExternalLink www.trpchannel.org.
- TRPML wikiPageID "11896846".
- TRPML wikiPageRevisionID "593219499".
- TRPML hasPhotoCollection TRPML.
- TRPML subject Category:Ion_channels.
- TRPML subject Category:Membrane_biology.
- TRPML type Abstraction100002137.
- TRPML type Act100030358.
- TRPML type Channel106259898.
- TRPML type Communication106252138.
- TRPML type Event100029378.
- TRPML type IonChannels.
- TRPML type PsychologicalFeature100023100.
- TRPML type Transmission106251781.
- TRPML type YagoPermanentlyLocatedEntity.
- TRPML comment "TRPML (transient receptor potential cation channel, mucolipin subfamily) comprises a group of three evolutionarily related proteins that belongs to the large family of transient receptor potential ion channels. The three proteins TRPML1, TRPML2 and TRPML3 are encoded by the mucolipin-1 (MCOLN1), mucolipin-2 (MCOLN2) and mucolipin-3 (MCOLN3) genes, respectively. The three members of the TRPML ("ML" for mucolipin) sub-family are not extremely well characterized.".
- TRPML label "TRPML".
- TRPML sameAs m.02rx6ck.
- TRPML sameAs Q7671483.
- TRPML sameAs Q7671483.
- TRPML sameAs TRPML.
- TRPML wasDerivedFrom TRPML?oldid=593219499.
- TRPML isPrimaryTopicOf TRPML.