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- Tasimelteon abstract "Tasimelteon (trade name Hetlioz, previously known as BMS-214,778) is a drug approved solely for the treatment of non-24-hour sleep–wake disorder in totally blind people. It was under development for the treatment of insomnia and other sleep disorders. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to older drugs such as ramelteon. It has been through Phase III trials successfully and was shown to improve both onset and maintenance of sleep, with few side effects.A year-long (2011–2012) study at Harvard tested the use of tasimelteon in blind subjects with non-24-hour sleep–wake disorder. In May 2013 Vanda Pharmaceuticals submitted a New Drug Application to the Food and Drug Administration for tasimelteon for the treatment of non-24-hour sleep–wake disorder in totally blind people. It was approved by the FDA on January 31, 2014 under the brand name Hetlioz.".
- Tasimelteon atcPrefix "none".
- Tasimelteon casNumber "609799-22-6".
- Tasimelteon fdaUniiCode "SHS4PU80D9".
- Tasimelteon iupacName "(1R, 2R)-N-[2-(2,3-dihydrobenzofuran-4-yl)cyclopropylmethyl]propanamide".
- Tasimelteon pubchem "10220503".
- Tasimelteon thumbnail Tasimelteon_2.svg?width=300.
- Tasimelteon wikiPageExternalLink www.hetlioz.com.
- Tasimelteon wikiPageID "20514003".
- Tasimelteon wikiPageRevisionID "601100884".
- Tasimelteon atcPrefix "none".
- Tasimelteon bioavailability "not determined in humans".
- Tasimelteon c "15".
- Tasimelteon casNumber "609799".
- Tasimelteon chemspiderid "8395995".
- Tasimelteon eliminationHalfLife "21240.0".
- Tasimelteon excretion "80".
- Tasimelteon h "19".
- Tasimelteon hasPhotoCollection Tasimelteon.
- Tasimelteon inchi "1".
- Tasimelteon inchikey "PTOIAAWZLUQTIO-GXFFZTMABK".
- Tasimelteon iupacName "-N-[2-cyclopropylmethyl]propanamide".
- Tasimelteon legalUs "Rx-only".
- Tasimelteon metabolism "extensive hepatic, primarily CYP1A2 and CYP3A4-mediated".
- Tasimelteon molecularWeight "245.32".
- Tasimelteon n "1".
- Tasimelteon o "2".
- Tasimelteon pregnancyUs "C".
- Tasimelteon proteinBound "89".
- Tasimelteon pubchem "10220503".
- Tasimelteon routesOfAdministration "Oral".
- Tasimelteon smiles "CCCNC[C@@H]1C[C@H]1C2=C3CCOC3=CC=C2".
- Tasimelteon stdinchi "1".
- Tasimelteon stdinchikey "PTOIAAWZLUQTIO-GXFFZTMASA-N".
- Tasimelteon tradename "Hetlioz".
- Tasimelteon unii "SHS4PU80D9".
- Tasimelteon verifiedrevid "448209779".
- Tasimelteon watchedfields "changed".
- Tasimelteon width "230".
- Tasimelteon subject Category:Benzofurans.
- Tasimelteon subject Category:Cyclopropanes.
- Tasimelteon subject Category:Propionamides.
- Tasimelteon subject Category:Sedatives.
- Tasimelteon type Agent114778436.
- Tasimelteon type Anesthetic102710766.
- Tasimelteon type CausalAgent100007347.
- Tasimelteon type Cyclopropane103155661.
- Tasimelteon type Cyclopropanes.
- Tasimelteon type Drug103247620.
- Tasimelteon type DrugOfAbuse103248958.
- Tasimelteon type GeneralAnesthetic103433434.
- Tasimelteon type InhalationAnesthetic103570838.
- Tasimelteon type Matter100020827.
- Tasimelteon type Medicine103740161.
- Tasimelteon type PhysicalEntity100001930.
- Tasimelteon type Sedative104166553.
- Tasimelteon type Sedatives.
- Tasimelteon type Substance100020090.
- Tasimelteon type Drug.
- Tasimelteon type DrugProduct.
- Tasimelteon type FunctionalSubstance.
- Tasimelteon comment "Tasimelteon (trade name Hetlioz, previously known as BMS-214,778) is a drug approved solely for the treatment of non-24-hour sleep–wake disorder in totally blind people. It was under development for the treatment of insomnia and other sleep disorders. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to older drugs such as ramelteon.".
- Tasimelteon label "Tasimelteon".
- Tasimelteon sameAs m.051_y8b.
- Tasimelteon sameAs Q7687250.
- Tasimelteon sameAs Q7687250.
- Tasimelteon sameAs Tasimelteon.
- Tasimelteon wasDerivedFrom Tasimelteon?oldid=601100884.
- Tasimelteon depiction Tasimelteon_2.svg.
- Tasimelteon isPrimaryTopicOf Tasimelteon.
