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- Testis_determining_factor abstract "Testis-determining factor (TDF), also known as Sex-determining region Y (SRY) protein, is a DNA-binding protein encoded by the SRY gene that is responsible for the initiation of male sex determination in humans. SRY is an intronless sex-determining gene on the Y chromosome in the therians (placental mammals and marsupials), and mutations in this gene lead to a range of sex-related disorders with varying effects on an individual's phenotype and genotype. TDF is a member of the SOX (SRY-like box) gene family of DNA-binding proteins. When complexed with the SF1 protein, TDF acts as a transcription factor that can upregulate other transcription factors, most importantly SOX9. Its expression causes the development of primary sex cords, which later develop into seminiferous tubules. These cords form in the central part of the yet-undifferentiated gonad, turning it into a testis. The now induced Leydig cells of the testis then start secreting testosterone while the Sertoli cells produce anti-Mullerian hormone.".
- Testis_determining_factor entrezgene "6736".
- Testis_determining_factor wikiPageExternalLink NBK1416.
- Testis_determining_factor wikiPageExternalLink 278850,480000,278850,480000.
- Testis_determining_factor wikiPageID "1475503".
- Testis_determining_factor wikiPageRevisionID "605976592".
- Testis_determining_factor hasPhotoCollection Testis_determining_factor.
- Testis_determining_factor subject Category:Epigenetics.
- Testis_determining_factor subject Category:Genes_on_chromosome_Y.
- Testis_determining_factor subject Category:Human_genes.
- Testis_determining_factor subject Category:Mammal_genes.
- Testis_determining_factor subject Category:Transcription_factors.
- Testis_determining_factor type Abstraction100002137.
- Testis_determining_factor type Arrangement107938773.
- Testis_determining_factor type Gene105436752.
- Testis_determining_factor type Genes.
- Testis_determining_factor type Group100031264.
- Testis_determining_factor type Ordering108456993.
- Testis_determining_factor type Sequence108459252.
- Testis_determining_factor type Series108457976.
- Testis_determining_factor type Biomolecule.
- Testis_determining_factor type Protein.
- Testis_determining_factor type BiologicalObject.
- Testis_determining_factor comment "Testis-determining factor (TDF), also known as Sex-determining region Y (SRY) protein, is a DNA-binding protein encoded by the SRY gene that is responsible for the initiation of male sex determination in humans. SRY is an intronless sex-determining gene on the Y chromosome in the therians (placental mammals and marsupials), and mutations in this gene lead to a range of sex-related disorders with varying effects on an individual's phenotype and genotype.".
- Testis_determining_factor label "Facteur déterminant des testicules".
- Testis_determining_factor label "Hoden-determinierender Faktor".
- Testis_determining_factor label "TDF (gene)".
- Testis_determining_factor label "Testis determining factor".
- Testis_determining_factor label "Фактор TDF".
- Testis_determining_factor sameAs Hoden-determinierender_Faktor.
- Testis_determining_factor sameAs Facteur_déterminant_des_testicules.
- Testis_determining_factor sameAs TDF_(gene).
- Testis_determining_factor sameAs 고환결정인자.
- Testis_determining_factor sameAs m.054ghq.
- Testis_determining_factor sameAs Q413911.
- Testis_determining_factor sameAs Q413911.
- Testis_determining_factor sameAs Testis_determining_factor.
- Testis_determining_factor wasDerivedFrom Testis_determining_factor?oldid=605976592.
- Testis_determining_factor isPrimaryTopicOf Testis_determining_factor.