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- Thiolutin abstract "Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability. Studies have shown that thiolutin inhibits adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin and thus suppresses tumor cell-induced angiogenesis in vivo.Thiolutin is formed in submerged fermentation by several strains of Streptomycetes luteosporeus. Some sources erroneously specify "aureothricin" as a synonym of thiolutin. Aureothricin is an antibiotic very similar to thiolutin, and is created as a by-product during the thiolutin fermentation.".
- Thiolutin atcPrefix "none".
- Thiolutin casNumber "87-11-6".
- Thiolutin iupacName "N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide".
- Thiolutin pubchem "6870".
- Thiolutin thumbnail Thiolutin.png?width=300.
- Thiolutin wikiPageID "12083623".
- Thiolutin wikiPageRevisionID "593180609".
- Thiolutin atcPrefix "none".
- Thiolutin c "8".
- Thiolutin casNumber "87".
- Thiolutin chembl "507026".
- Thiolutin chemspiderid "6608".
- Thiolutin h "8".
- Thiolutin hasPhotoCollection Thiolutin.
- Thiolutin inchi "1".
- Thiolutin inchikey "MHMRAFONCSQAIA-UHFFFAOYAX".
- Thiolutin iupacName "N-acetamide".
- Thiolutin molecularWeight "228.293".
- Thiolutin n "2".
- Thiolutin o "2".
- Thiolutin pubchem "6870".
- Thiolutin s "2".
- Thiolutin smiles "O=CC".
- Thiolutin stdinchi "1".
- Thiolutin stdinchikey "MHMRAFONCSQAIA-UHFFFAOYSA-N".
- Thiolutin synonyms "(N-acetamide, farcinicin, propiopyvothine, acetopyrrothine)".
- Thiolutin verifiedfields "changed".
- Thiolutin verifiedrevid "470607244".
- Thiolutin subject Category:Acetamides.
- Thiolutin subject Category:Antibiotics.
- Thiolutin subject Category:Lactams.
- Thiolutin subject Category:Organic_disulfides.
- Thiolutin type Abstraction100002137.
- Thiolutin type Acetamide114711197.
- Thiolutin type Acetamides.
- Thiolutin type Amide114724264.
- Thiolutin type Chemical114806838.
- Thiolutin type Compound114818238.
- Thiolutin type Material114580897.
- Thiolutin type Matter100020827.
- Thiolutin type OrganicCompound114727670.
- Thiolutin type Part113809207.
- Thiolutin type PhysicalEntity100001930.
- Thiolutin type Relation100031921.
- Thiolutin type Substance100019613.
- Thiolutin type Drug.
- Thiolutin type DrugProduct.
- Thiolutin type FunctionalSubstance.
- Thiolutin comment "Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability.".
- Thiolutin label "Thiolutin".
- Thiolutin sameAs m.02vp8vx.
- Thiolutin sameAs Q7784674.
- Thiolutin sameAs Q7784674.
- Thiolutin sameAs Thiolutin.
- Thiolutin wasDerivedFrom Thiolutin?oldid=593180609.
- Thiolutin depiction Thiolutin.png.
- Thiolutin isPrimaryTopicOf Thiolutin.