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- Troglitazone abstract "Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones. It was prescribed for patients with diabetes mellitus type 2. It was developed by Daiichi Sankyo Co.(Japan). In the United States, it was introduced and manufactured by Parke-Davis in the late 1990s, but turned out to be associated with an idiosyncratic reaction leading to drug-induced hepatitis. One F.D.A. medical officer evaluating troglitazone, John Gueriguian, did not recommend its approval due to potential high liver toxicity, but a full panel of experts approved it in January 1997. Once the prevalence of adverse liver effects became known, troglitazone was withdrawn from the British market in December 1997, from the United States market in 2000, and from the Japanese market soon afterwards. It didn't get approval in the rest of Europe.".
- Troglitazone atcPrefix "A10".
- Troglitazone atcSuffix "BG01".
- Troglitazone casNumber "97322-87-7".
- Troglitazone chEBI "9753".
- Troglitazone drugbank "DB00197".
- Troglitazone fdaUniiCode "I66ZZ0ZN0E".
- Troglitazone iupacName "(RS)-5-(4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl)thiazolidine-2,4-dione".
- Troglitazone pubchem "5591".
- Troglitazone thumbnail Troglitazone_structure.png?width=300.
- Troglitazone wikiPageExternalLink rezulin.htm.
- Troglitazone wikiPageExternalLink troglitazone.htm.
- Troglitazone wikiPageID "597793".
- Troglitazone wikiPageRevisionID "605423206".
- Troglitazone atcPrefix "A10".
- Troglitazone atcSuffix "BG01".
- Troglitazone c "24".
- Troglitazone casNumber "97322".
- Troglitazone chebi "9753".
- Troglitazone chembl "408".
- Troglitazone chemspiderid "5389".
- Troglitazone drugName "Troglitazone".
- Troglitazone drugbank "DB00197".
- Troglitazone eliminationHalfLife "-122400.0".
- Troglitazone h "27".
- Troglitazone hasPhotoCollection Troglitazone.
- Troglitazone imagename "Chemical structure of troglitazone".
- Troglitazone inchi "1".
- Troglitazone inchikey "GXPHKUHSUJUWKP-UHFFFAOYAV".
- Troglitazone iupacName "-5".
- Troglitazone iupharLigand "2693".
- Troglitazone kegg "D00395".
- Troglitazone molecularWeight "441.541".
- Troglitazone n "1".
- Troglitazone o "5".
- Troglitazone pubchem "5591".
- Troglitazone s "1".
- Troglitazone smiles "O=C1NCSC1Cc4ccccc4".
- Troglitazone stdinchi "1".
- Troglitazone stdinchikey "GXPHKUHSUJUWKP-UHFFFAOYSA-N".
- Troglitazone unii "I66ZZ0ZN0E".
- Troglitazone verifiedfields "changed".
- Troglitazone verifiedrevid "470617744".
- Troglitazone width "220".
- Troglitazone subject Category:Chromanes.
- Troglitazone subject Category:Phenol_ethers.
- Troglitazone subject Category:Phenols.
- Troglitazone subject Category:Thiazolidinediones.
- Troglitazone subject Category:Withdrawn_drugs.
- Troglitazone type Abstraction100002137.
- Troglitazone type Chemical114806838.
- Troglitazone type Compound114818238.
- Troglitazone type Element114840755.
- Troglitazone type Material114580897.
- Troglitazone type Matter100020827.
- Troglitazone type OrganicCompound114727670.
- Troglitazone type Part113809207.
- Troglitazone type Phenol114989545.
- Troglitazone type PhenolEthers.
- Troglitazone type Phenols.
- Troglitazone type PhysicalEntity100001930.
- Troglitazone type Quintessence114847103.
- Troglitazone type Relation100031921.
- Troglitazone type Substance100019613.
- Troglitazone type Drug.
- Troglitazone type DrugProduct.
- Troglitazone type FunctionalSubstance.
- Troglitazone comment "Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones. It was prescribed for patients with diabetes mellitus type 2. It was developed by Daiichi Sankyo Co.(Japan). In the United States, it was introduced and manufactured by Parke-Davis in the late 1990s, but turned out to be associated with an idiosyncratic reaction leading to drug-induced hepatitis. One F.D.A.".
- Troglitazone label "Troglitazona".
- Troglitazone label "Troglitazone".
- Troglitazone sameAs Troglitazona.
- Troglitazone sameAs m.02ty4c.
- Troglitazone sameAs Q7844989.
- Troglitazone sameAs Q7844989.
- Troglitazone sameAs DB00197.
- Troglitazone sameAs 5591.
- Troglitazone sameAs Troglitazone.
- Troglitazone wasDerivedFrom Troglitazone?oldid=605423206.
- Troglitazone depiction Troglitazone_structure.png.
- Troglitazone isPrimaryTopicOf Troglitazone.
- Troglitazone name "Troglitazone".