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- Type_II_hypersensitivity abstract "In type II hypersensitivity (or cytotoxic hypersensitivity) the antibodies produced by the immune response bind to antigens on the patient's own cell surfaces. The antigens recognized in this way may either be intrinsic ("self" antigen, innately part of the patient's cells) or extrinsic (adsorbed onto the cells during exposure to some foreign antigen, possibly as part of infection with a pathogen). These cells are recognized by macrophages or dendritic cells, which act as antigen-presenting cells. This causes a B cell response, wherein antibodies are produced against the foreign antigen.An example of type II hypersensitivity is the reaction to penicillin wherein the drug can bind to red blood cells, causing them to be recognized as different; B cell proliferation will take place and antibodies to the drug are produced. IgG and IgM antibodies bind to these antigens to form complexes that activate the classical pathway of complement activation to eliminate cells presenting foreign antigens (which are usually, but not in this case, pathogens). That is, mediators of acute inflammation are generated at the site and membrane attack complexes cause cell lysis and death. The reaction takes hours to a day.Another example of type II hypersensitivity reaction is Goodpasture's syndrome where the basement membrane(containing collagen type IV) in the lung and kidney is attacked by our own antibodies.Another form of type II hypersensitivity is called antibody-dependent cell-mediated cytotoxicity (ADCC). Here, cells exhibiting the foreign antigen are tagged with antibodies (IgG or IgM). These tagged cells are then recognised by natural killer cells (NK) and macrophages (recognised via IgG bound (via the Fc region) to the effector cell surface receptor, CD16 (FcγRIII)), which in turn kill these tagged cells.".
- Type_II_hypersensitivity diseasesdb "33482".
- Type_II_hypersensitivity medlineplus "000821".
- Type_II_hypersensitivity meshId "D001327".
- Type_II_hypersensitivity wikiPageID "15167037".
- Type_II_hypersensitivity wikiPageRevisionID "603217671".
- Type_II_hypersensitivity diseasesdb "33482".
- Type_II_hypersensitivity hasPhotoCollection Type_II_hypersensitivity.
- Type_II_hypersensitivity medlineplus "821".
- Type_II_hypersensitivity meshid "D001327".
- Type_II_hypersensitivity subject Category:Hypersensitivity.
- Type_II_hypersensitivity type Abstraction100002137.
- Type_II_hypersensitivity type Attribute100024264.
- Type_II_hypersensitivity type Condition113920835.
- Type_II_hypersensitivity type Disease114070360.
- Type_II_hypersensitivity type IllHealth114052046.
- Type_II_hypersensitivity type Illness114061805.
- Type_II_hypersensitivity type PathologicalState114051917.
- Type_II_hypersensitivity type PhysicalCondition114034177.
- Type_II_hypersensitivity type State100024720.
- Type_II_hypersensitivity type Disease.
- Type_II_hypersensitivity type AilmentCondition.
- Type_II_hypersensitivity type Situation.
- Type_II_hypersensitivity comment "In type II hypersensitivity (or cytotoxic hypersensitivity) the antibodies produced by the immune response bind to antigens on the patient's own cell surfaces. The antigens recognized in this way may either be intrinsic ("self" antigen, innately part of the patient's cells) or extrinsic (adsorbed onto the cells during exposure to some foreign antigen, possibly as part of infection with a pathogen).".
- Type_II_hypersensitivity label "Hipersensibilidad de tipo II".
- Type_II_hypersensitivity label "Type II hypersensitivity".
- Type_II_hypersensitivity sameAs Hipersensibilidad_de_tipo_II.
- Type_II_hypersensitivity sameAs m.0466py0.
- Type_II_hypersensitivity sameAs Q5898312.
- Type_II_hypersensitivity sameAs Q5898312.
- Type_II_hypersensitivity sameAs Type_II_hypersensitivity.
- Type_II_hypersensitivity wasDerivedFrom Type_II_hypersensitivity?oldid=603217671.
- Type_II_hypersensitivity isPrimaryTopicOf Type_II_hypersensitivity.