Matches in DBpedia 2014 for { <http://dbpedia.org/resource/UBR1> ?p ?o. }
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- UBR1 abstract "The human gene UBR1 encodes the enzyme ubiquitin-protein ligase E3 component n-recognin 1.The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.".
- UBR1 entrezgene "197131".
- UBR1 wikiPageID "14817264".
- UBR1 wikiPageRevisionID "593228212".
- UBR1 hasPhotoCollection UBR1.
- UBR1 requireManualInspection "no".
- UBR1 summaryText "The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.".
- UBR1 updateCitations "yes".
- UBR1 updatePage "yes".
- UBR1 updateProteinBox "yes".
- UBR1 updateSummary "yes".
- UBR1 type Biomolecule.
- UBR1 type Protein.
- UBR1 type BiologicalObject.
- UBR1 comment "The human gene UBR1 encodes the enzyme ubiquitin-protein ligase E3 component n-recognin 1.The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein.".
- UBR1 label "UBR1".
- UBR1 label "UBR1".
- UBR1 label "Ubiquitin-Protein-Ligase UBR1".
- UBR1 sameAs Ubiquitin-Protein-Ligase_UBR1.
- UBR1 sameAs UBR1.
- UBR1 sameAs m.03gyz8p.
- UBR1 sameAs Q425793.
- UBR1 sameAs Q425793.
- UBR1 wasDerivedFrom UBR1?oldid=593228212.
- UBR1 isPrimaryTopicOf UBR1.