Matches in DBpedia 2014 for { <http://dbpedia.org/resource/UPF2> ?p ?o. }
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- UPF2 abstract "Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.This gene encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.".
- UPF2 entrezgene "26019".
- UPF2 wikiPageID "14761960".
- UPF2 wikiPageRevisionID "593239657".
- UPF2 hasPhotoCollection UPF2.
- UPF2 requireManualInspection "no".
- UPF2 summaryText "This gene encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay . When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.".
- UPF2 updateCitations "yes".
- UPF2 updatePage "yes".
- UPF2 updateProteinBox "yes".
- UPF2 updateSummary "yes".
- UPF2 type Biomolecule.
- UPF2 type Protein.
- UPF2 type BiologicalObject.
- UPF2 comment "Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.This gene encodes a protein that is part of a post-splicing multiprotein complex, the exon junction complex, involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).".
- UPF2 label "UPF2".
- UPF2 sameAs m.03gx2rg.
- UPF2 sameAs Q7865487.
- UPF2 sameAs Q7865487.
- UPF2 wasDerivedFrom UPF2?oldid=593239657.
- UPF2 isPrimaryTopicOf UPF2.